Here's my application,I think I'd be a very good fit,I'll start off with a bit of my background and training history....
I',m 37 and have been training since the age of 25.I have a thorough grasp on physique/performance enhancement supplements,having done more than my fair share of pro hormones,as well as cough,cough...scheduled hormones.I regularly peruse the forums and Pubmed to further my understanding of such (legal) compounds and how to best utilize them in a safe manner.
In my more a-hem,illustrious past,I have used testosterone,anavar,deca,NPP and masteron.Modeate dosing of shorter estered test + var being my personal favorite.
Nowadays I stick to the legal compounds and with the demise of PP's lineup,I was happy to see that Andro factory offered fairly similiar compounds at decent price points.I've been running AF's Focus along with Lean Cut for the past 3 weeks and am overall very impressed.Considering the illicit compounds I've used in the past,that is a fairly bold statement that should carry a decent amount of weight.Focus feels like a test base,speaking in terms of enhanced cognitive processing and recovery whilst staving off lethargy which is commonly associated with pro-hormonal compounds.
PH's I've ran in the past include 1-T Tren ,Havoc,X-Tren,P-Mag,NorDerm and about half of the AMS & Fore Runner lineup.
Andro Factory is the first company to come along since AMS,Fore Runner and PP,which primarily offers pro-hormonals,that I find to be respectful of athletes and to be on the level so I would be honored to act as a product rep for AF.
I've been around the forums on a fairly regular basis for about a decade.I'm 37 and I have been training since the age of 23.I have posted much more on mindandmuscle.net/forums than AM as I was an Acant Labs board rep for over 2 years.Moreso to the point,back in the day,M&M was the most scientific based board and that is what inspired me to delve into Pubmed abstracts and the like.
I feel that my experience in both the realms of training and supplementation would make for a valuable addition to the AF team,considering I could help guide both older lifters like myself and younger guys towards their goals with what I've learned first hand,over the years.
In addition to Avant Labs,I have previously repped for Purus Labs and Live Long Nutrition.
I handled more than just basic rep duties at all of the companies I acted as a board rep for,such as drafting product writeups For Live Long Nutrition,which I will post up a copy of below....just to show that I am capable of intelligent thought
I'll go one step beyond that and post up a link to a thread on BB.com,which shows a slew of my posts as a Live Long rep,wherein I brought the effing science.I'm posting these links to show that I'm not the kind of guy who would be a subpar rep for AF,urging other board members to buy AF product on the grounds it'll make you soooper hyuuuge and ripped.In other words,I'm not big on bro-science
http://forum.bodybuilding.com/showthread.php?t=110062511&page=1
Foocox-10 & Burning The White Stuff
By Colin O'Malley
Please divulge me in my prefacing of this article with the expression of heartfelt love (yes,I'm over reaching here but its for a good point) I have for uncoupling agents.Using such compounds have proven invaluable in my past cutting endeavors.However,not all of us are willing to run cycles of DNP and furthermore,heavy handed uncouplers tend to have harsh side effects and make dieting all the worse.Aye,DNP and usnic acid mediate their magical fat loss effects directly from the thirteenth plane of Hell.
New compounds that may be used safely at any time clearly should be researched and several compounds have recently come into light.One of the more promising agents is fucoxanthin.
In order to describe the benefits of mitochondrial uncoupling,I will elucidate the role that uncoupling plays in body composition.Energy balance in animals is a metabolic state that exists when total body energy expenditure equals dietary energy intake. Energy expenditure, or thermogenesis, can be subcategorized into groups of obligatory and facultative metabolic processes. Brown adipose tissue (BAT), through the activity of uncoupling protein 1 (UCP1), is responsible for nonshivering thermogenesis, a major component of facultative thermogenesis in newborn humans and in small mammals. UCP1, found in the mitochondrial inner membrane in BAT, uncouples energy substrate oxidation from mitochondrial ATP production and hence results in the loss of potential energy as heat. Mice that do not express UCP1 (UCP1 knockouts) are markedly cold sensitive. The recent identification of four new homologs to UCP1 expressed in BAT, muscle, white adipose tissue, brain, and other tissues has been met by tremendous scientific interest. The hypothesis that the novel UCPs may regulate thermogenesis and/or fatty acid metabolism guides investigations worldwide.
I will illustrate a compound that not only acts as an uncoupler (1) but as a life extension tool via its potent antioxidant capabilities (2) and holds promise as a treatment of cancer(3).It also is regarded as a tool in the war against metabolic Syndrome and has multiple other functions within the body (4).It goes beyond uncoupling with regard to fat loss as it actively supresses fat gain by putting a stopgap,so to speak,in the growth of new fat cells. (5) So we have not only all of these attributes to weigh but another very big plus in fucoxanthin's column is that fucoxanthin chiefly manipulates UCP1,which bears nearly the sole impact on fat loss out of UCP1,UCP2 and UCP3 (6).
So we have established that fucoxanthin acts chiefly on UCP1 and this is primarily responsible for its application towards improving body composition.However,there is a large problem with fucoxathin,which no one has addressed yet in product formulation or even stack suggestions.This would be subpar oral bioavalability (7).If a product isn't orally bioavailable,little good will come of its use and thus,we are wasting our time and money.However,this issue can be easily circumvented if fucoxathin is taken with fat,MCT oil (8) and fish oil (9) serve as prime examples but any other form of fat will d
bviously,if fish oil or MCT oil are not utilized,one should use a a desirable fat source that confers other beneficial properties e.g. Enova,sesamin,CLA,olive oil,flax seed oil,lecithin and so on.
Fucoxathin has several quite synergystic angles to exploit,Sesathin being one of them. PPAR-alpha agonism via Sesathin combined with PPARg antagonism would be great. The perfect combo would be PPAR-alpha agonism with gamma antagonism in adipocytes but gamma agonism in other tissues. This is essentially what SIRT-1 activation does in regards to gamma.
Guanidinopropionic Acid,Green Tea Extract and Salvia miltiorrhiza would also be just about the ideal complimentary choices in addition to Resveratrol.The latter would serve to further activate SIRT-1 while the former compounds in essence potentiate attainable benefits through quite a stunning layout of synergystic activity.
References:
1)
Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues.
Maeda H, Hosokawa M, Sashima T, Funayama K, Miya****a K.
Laboratory of Biofunctional Material Chemistry, Division of Marine Bioscience, Graduate School of Fisheries Sciences, Hokkaido University, Hakodate, Hokkaido 041-8611, Japan.
PMID: 15896707
2)
Radical scavenging and singlet oxygen quenching activity of marine carotenoid fucoxanthin and its metabolites.
Sachindra NM, Sato E, Maeda H, Hosokawa M, Niwano Y, Kohno M, Miya****a K.
Faculty of Fisheries, Hokkaido University, 3-1-1 Minato, Hakodate 041-8611, Japan.
PMID: 17894451
3)
Antiadult T-cell leukemia effects of brown algae fucoxanthin and its deacetylated product, fucoxanthinol.
Ishikawa C, Tafuku S, Kadekaru T, Sawada S, Tomita M, Okudaira T, Nakazato T, Toda T, Uchihara JN, Taira N, Ohshiro K, Yasumoto T, Ohta T, Mori N.
Division of Molecular Virology and Oncology, Graduate School of Medicine, University of the Ryukyus, Nishihara, Okinawa, Japan.
PMID: 18798263
4)
Seaweed carotenoid, fucoxanthin, as a multi-functional nutrient.
Maeda H, Tsukui T, Sashima T, Hosokawa M, Miya****a K.
Faculty of Fisheries Sciences, Hokkaido University, Hakodate 041-8611, Japan.
PMID: 18296336
5)
Fucoxanthin and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells.
Maeda H, Hosokawa M, Sashima T, Takahashi N, Kawada T, Miya****a K.
Faculty of Fisheries Sciences, Hokkaido University, Hakodate, Hokkaido 041-8611, Japan.
PMID: 16786166
6)
UCP1: the only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency.
Nedergaard J, Golozoubova V, Matthias A, Asadi A, Jacobsson A, Cannon B.
The Wenner-Gren Institute, The Arrhenius Laboratories F3, Stockholm University, SE-106 91 Stockholm, Sweden.
[email protected]
PMID: 11239487
7)
Low bioavailability of dietary epoxyxanthophylls in humans.
Asai A, Yonekura L, Nagao A.
National Food Research Institute, NARO, 2-1-12 Kannondai, Tsukuba, Ibaraki 305-8642, Japan.
PMID: 18186952
8)
Effect of medium-chain triacylglycerols on anti-obesity effect of fucoxanthin.
Maeda H, Hosokawa M, Sashima T, Funayama K, Miya****a K.
Faculty of Fisheries Sciences, Hokkaido University, Hokkaido, Japan.
[email protected]
PMID: 17992001
9)
Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic KK-Ay mice.
Maeda H, Hosokawa M, Sashima T, Miya****a K.
Faculty of Fisheries Sciences, Hokkaido University, 3-1-1 Minato, Hakodate, Hokkaido 041-8611, Japan.
PMID: 17715888
