PES Erase Pro - The Breakdown

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    PES Erase Pro - The Breakdown


    After more than a years worth of phenomenal feedback on Erase, we have decided to formulate an all new, full spectrum, hardcore product - Erase Pro.

    Erase will not be going anywhere...but you will now have the option to take the Erase experience to a whole new level.

    Erase Pro utilizes hormone modulation like never before. With the addition of two new very exciting ingredients users will experience effects they never even imagined possible with an OTC product.

    As a standalone, Erase Pro simultaneously has both AI and SERM-like properties. It can act both as an aromatase inhibitor and as an estrogen receptor antagonist.

    Aromatase inhibition is sought after due to the fact that by inhibiting the conversion of testosterone to estrogen, T goes up and E goes down.

    SERMs are sought after because they block estrogen itself from binding to and activating its receptor. By doing this your body senses a need for more estrogen. Since estrogen comes from testosterone, your body signals for more and more testosterone release. This is why SERMs are used heavily in the underground bodybuilding community.

    An ingredient in Erase Pro also has animal data on cortisol reduction. Keep the cortisol spike down. You may choose to take your Erase Pro in the morning, or around your workouts. Times when cortisol is highest...be both anabolic and anti-catabolic.

    For users of anabolics, this is the absolute best combination of mechanisms for an over the counter PCT. You can see why, with the combination of both AI and ER inhibition. That is how PCTs are designed.

    So what can you expect from Erase Pro over Erase?

    Even greater physiological effects. We know because we tested it extensively. We had a number of possible ingredients with possible SERM action, and the one we used clearly stood out to us. We spent the time to find the best extraction and the best dose to combine with the Androsta-3,5-diene-7,17-dione.

    We have more experience with the original Erase ingredient than anyone...and there is no doubt Erase Pro's formula took the feel to a new level.

    Everyone loves the hardening, drying, lean feeling Erase gives. Expect all that and more from Erase Pro.

    The writeup can be viewed on our website, www.pescience.com
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    Boerhaavia diffusa (Root) Extract




    Anti-Estrogen via direct Estrogen Receptor Binding

    B. diffusa showed potent competitive binding for the estrogen receptor in vitro. The result was less estrogen could bind to the receptor. By preventing E from binding to its receptor it cannot give its undesirable effects on the body.

    This is the same mechanism SERMs like Nolva use. As a result your body will signal for more testosterone release in order to hope to also increase estrogen. This is why we included an aromatase inhibitor in Erase Pro.

    (Sreekumar Sreeja, Sreeharshan Sreeja; An in vitro study on antiproliferative and antiestrogenic effects of Boerhaavia diffusa L. extracts Journal of Ethnopharmacology, Volume 126, Issue 2, 12 November 2009, Pages 221-225)



    Cortisol Modulation in the Animal Model

    Data shows that in a stress swim test, animals taking BDE (b. diffusa extract) did not see the significant estrogen spike that control groups saw. The BDE group also had 25% longer swimming times.

    Cortisol is the hormone released is stressful situations, especially during physical training. This catabolic hormone has the ability to break down muscle. BDE gives Erase Pro a true anti-catabolic mechanism

    (Meera Sumanth and S.S. Mustafa, Antistress, Adaptogenic and Immunopotentiating Activity Roots of Boerhaavia Diffusa in Mice, International Journal of Pharmacology 3 (5): 416-420, 2007)



    Diuretic Activity

    BDE has also shown to have direct diuretic activity. This fits perfectly in the goal of Erase Pro. Lean...Dry...Hard.

    (Gaitonde, B.B., Kulkarni, H.J., and Nabar,S.D. Diuretic activity of punarnava (Boerhaavia diffusa). Bulletins of the Haffkine Institute (Bombay,India) 1974; 2:24)


    Alpha-2 Adrenergic Antagonist

    You may be familiar with this mechanism if you have real about Alpha-T2, as it is the target pathway in Alpha-T2. Alpha-2 adrenoceptors are receptors in the stomach, love handles, and chest that when turned on are working to STORE fat in those areas. By inhibiting this enzyme you can turn the mechanism off. This is the key pathway to targeted fat loss, most especially belly fat.

    (Shigetoshi Kadota et al. Constituents of the Roots of Boerhaavia diffusa L. I. Examination of Sterols and Structures of New Rotenoids, Boerhavinones A and B; Chem Pharm Bull 37(12) 3214-3220 (1989) Vol. 37 No. 12)
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    Euonymus alatus (Root) Extract





    This ingredient caters to those who will be using Erase Pro on cycle and/or PCT. It works under a mechanism known as in-situ inhibition of estrogen. This mechanism is on the forefront of research for developing a way to target estrogen reduction selectively in breast cancer patients.

    Those who cycle know that some people are super prone to gyno and seem almost gyno-invincible. The cause of this is some people have more aromatase enzymes in their mammary cells than others.

    This ingredient and its mechanism may hold the key to making those who are extremely prone to on-cycle or PCT gyno much less susceptible.

    (Lee TK, Kim DI, Han JY, Kim CH. Inhibitory effects of Scutellaria barbata D. Don. and Euonymus alatus Sieb. on aromatase activity of human leiomyomal cells. Immunopharmacol Immunotoxicol. 2004 Aug;26(3):315-27.)
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    Androsta-3,5-diene-7,17-dione




    You guys all already know and love this compound so much...the majority of you have used it. We have given this ingredient at the favorite dose after a years worth of feedback - 75mg per capsule.

    Once daily dosing is all you need. In fact, if you find Erase Pro is too strong for you then you can even go to once every other day dosing.

    This amazing ingredient is a real, synthetic, irreversible aromatase inhibitor. The data shows a Ki value even better than exemestane, and way better than formestane.

    Erase, and this ingredient, are both so popular because of one reason...it works...and works extremely well. 1 capsule of Erase Pro is all you need...how's that for potent?

    Each of these ingredients are beasts of their own. We have tested the ingredients singularly and in concert with one another. The result is a truly special and cutting edge hardcore formula.

    For serious users only...no matter your goals. It is the ultimate hardening, drying, lean formula you will come across. Use it on bulk, cut, or recomp. You will feel the difference.

    (Numazawa M, Mutsumi A, Tachibana M, Hoshi K; Synthesis of androst-5-en-7-ones and androsta-3,5-dien-7-ones and their related 7-deoxy analogs as conformational and catalytic probes for the active site of aromatase; J Med Chem. 1994 Jul 8;37(14):2198-2)

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    Sounds like a solid product. I've only read good things about the original Erase, can't wait to hear more about Pro.
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    Name:  howard-dean-8.jpg
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    MFW I read this
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    Reserved for free bottle.
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    Ingredient 1 updated
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    Quote Originally Posted by T-Bone View Post
    Reserved for free bottle.
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    Got Glycophase ...?


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    Subd. Wasn't sure it was possible to mAke erase better!
    "no failure is final, nor is any success"
    Follow my 2014 training and supps!
    http://anabolicminds.com/forum/workout-logs/240285-chedapaloozas-2014-training.html
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    Quote Originally Posted by J19891 View Post
    Name:  howard-dean-8.jpg
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    MFW I read this
    Megan Fox was stoked as well.

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    Alpha 2 adrenergic activity on top or cortisol control, ai, and serm properties. holy ****, this will make a mean fat loss agent
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    Quote Originally Posted by mr.cooper69 View Post
    Alpha 2 adrenergic activity on top or cortisol control, ai, and serm properties. holy ****, this will make a mean fat loss agent
    A lean machine!
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    Nice! Looking forward to trying this one as well
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    I like it Natty, looks epic bro
    doing my own thang!
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    Natty any idea when your going to release this in the uk? I cants wait
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    Congrats on the new version Natty!

    Quick question (sorry if it has already been discussed on some other 3d): I remember
    reading something aboutAndrosta-3,5-diene-7,17-dione stimulating TSH,
    since I'm about to try to kickstart my thyroid levels (diet-induced drop)
    I'd like to hear your thoughts on this specific (proven?possible?) action of Androsta

    thanks bro!

    BTW just won a PES t-shirt on Fbbbbbbbbbbbb!!
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    Quote Originally Posted by AutoKal47 View Post
    Congrats on the new version Natty!

    Quick question (sorry if it has already been discussed on some other 3d): I remember
    reading something aboutAndrosta-3,5-diene-7,17-dione stimulating TSH,
    since I'm about to try to kickstart my thyroid levels (diet-induced drop)
    I'd like to hear your thoughts on this specific (proven?possible?) action of Androsta

    thanks bro!

    BTW just won a PES t-shirt on Fbbbbbbbbbbbb!!
    WHHAATT!! nice"! I want a T lol. Didnt even know they had a contest!
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    Quote Originally Posted by mattrag View Post
    WHHAATT!! nice"! I want a T lol. Didnt even know they had a contest!
    ah! I can send you a picture of it when I get it
    They're not even released yet, very first run and new design, some PES awesomenessssss
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    Reading this made me jizz my pants.

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    Damn! ERASE PRO?!

    Just started a log for my 14 week cut! What's a player got to do to log one of these?
    :blindfold:
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    I think this will be the product to pop my PES cherry! Haven't used any PES products yet, but I think this may be my first. Sounds right up my ally. I am currently dieting to drop bf.
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    did i hear testers are needed?

    LOL I am definitely going to order a bottle of this
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    Can't wait to get my hands on some.
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    Ooooooh, so wanting this as part of a spring pct....gimmie-gimmie-gimmie-I need-I need....
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    Sign me up! Man, still have 3 bottles of regular Erase I need to use.
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    I found out about this a few days ago when I got the latest planet muscle. Saw the ad and looked up the references
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    Quote Originally Posted by Robboe View Post
    I found out about this a few days ago when I got the latest planet muscle. Saw the ad and looked up the references
    Haha sneaky sneaky!
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    What about the test-boosting properties of Erase Pro? Comparable to Triazole? Or even better as standalone product?
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    Ingredient dos updated
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    Quote Originally Posted by uubiduu View Post
    What about the test-boosting properties of Erase Pro? Comparable to Triazole? Or even better as standalone product?
    Think SERM + AI combo.

    Very potent, in other words.
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    Ingredient 3 breakdown upgraded
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    I was on insider list...how come I havent got any email??
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    Quote Originally Posted by punjabimunde View Post
    I was on insider list...how come I havent got any email??
    Sometimes it takes a little longer for others to receive it.

    You can grab a link to the exact emailing from our facebook
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    Quote Originally Posted by punjabimunde View Post
    I was on insider list...how come I havent got any email??
    you sounded like the "I like taco's" guy on the commercial that had slow 3G service and got his invite to the taco party late lol
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    Quote Originally Posted by kevinhy

    Sometimes it takes a little longer for others to receive it.

    You can grab a link to the exact emailing from our facebook
    Ok cool...thanks
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    B. diffusa decreases testosterone so it's not very good for this kind of product
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    Quote Originally Posted by passenger View Post
    B. diffusa decreases testosterone so it's not very good for this kind of product
    Do your research. We sell the root, and a very specific extract. That study is on the leaf. Completely irrelevant.

    People dont smoke cannibas roots to get high.

    And we research what we are selling before we release it...
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    Quote Originally Posted by WARBIRDWS6 View Post
    you sounded like the "I like taco's" guy on the commercial that had slow 3G service and got his invite to the taco party late lol
    That was the commercial of the year!

    "I thought he gave you the creeps?"
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    Quote Originally Posted by nattydisaster

    Do your research. We sell the root, and a very specific extract. That study is on the leaf. Completely irrelevant.

    People dont smoke cannibas roots to get high.

    And we research what we are selling before we release it...
    PES blunt!!!!!!
  

  
 

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