Where's the acetyl resveratrol
- 04-19-2008, 06:15 PM
- 04-19-2008, 08:03 PM
- 04-19-2008, 09:10 PM
04-20-2008, 02:00 AM
04-20-2008, 02:53 AM
04-21-2008, 01:20 AM
04-21-2008, 07:55 AM
04-21-2008, 08:00 AM
i'm itching on this too, just to save me some $ over the cost of taking 1g of resveratrol a day. I think its around $2 a day which irritates me.
04-21-2008, 08:02 AM
04-21-2008, 08:04 AM
Oh I know, thats why i'm willing to spend $2 a day to take a high dose to get some oral availability
04-26-2008, 10:54 PM
Looking forward to trying this also, Anyone else get sleepy after taking resveratrol, if so just wondering what might cause this.
04-27-2008, 01:15 AM
04-27-2008, 09:49 PM
04-27-2008, 10:49 PM
I"m almost the same way. Caffeine does nothing but make me tired. I drink something with expresso and i damn near drop into a coma.
On a side note I can't wait for this one to come out. WIth an increase in bioavailability and a drop in price I think a lot more bb's will venture into using this for PCT.
04-27-2008, 11:25 PM
04-28-2008, 01:17 AM
04-28-2008, 01:23 AM
04-28-2008, 05:09 AM
Im quite excited also.For pct and general health this will be a VERY welcome addition to my supplement tackle box!
Trust in the LORD with all your heart, And lean not on your own understanding; In all your ways acknowledge Him, And He shall direct your paths . Proverbs 3:5-6
04-28-2008, 07:12 AM
04-28-2008, 07:27 AM
If you were going to use Resveratrol in a PCT how would the dosing be compared to just using it ed as a staple for general health?
Muscle Pharm Rep
04-29-2008, 10:50 AM
This is just speculation based on various opinions I've read, but i believe health benefits are seen with a low dose, such as 250 mg of trans-resveratrol daily. I myself haven't noticed much with such a low dose, but in the long-term it should be very beneficial as an anti-cancer/ anti-aging supplement.
For PCT, I was taking 1 gram daily of 98& trans-resveratrol with piperine for more bioavailabilty. I definately had more stamina and I could feel a marked improvment with libido after two weeks. I also dropped some boday fat, which was a nice side effect.
Honestly, you will want to exceed 1 gram dialy of the 98& resveratrol or 2 grams of the 50% extract for a good PCT.
With Ibe's new acetylated product coming, dosage can be smaller with much better bioavailabily. This is what I have been waiting for.
Hope that helps.
04-29-2008, 10:58 AM
04-29-2008, 10:14 PM
I don't know if Acetyl-Resveratrol is de-acetylated in vivo. I'd want to be certain that it is and activates SIRT1, among others. Sinclair's studies have shown that any deviation from the OH at the 4-position negated SIRT1 activity.
Last edited by riskarb; 04-29-2008 at 10:30 PM.
04-29-2008, 10:16 PM
04-29-2008, 11:59 PM
As for SIRT1 activation I have seen conflicting studies on it and at this point there just isn't enough information to say for sure that it is the only thing that is needed (4'-hydroxy). Plus, resveratrol has countless benefits that extend WELL beyond SIRT1 activation. In fact there are hundreds.
04-30-2008, 12:08 AM
04-30-2008, 01:05 AM
A plasma spike is seen prior to first pass. Is it bioavailable?
Sirtis had access to acetyl-resv and passed on it. As you know, there is virtually no in vitro activity with the acetyl form. Also, the acetyl is an NCE and therefore is not a natural product, rendering legal issues related to its sale.
04-30-2008, 11:56 AM
04-30-2008, 12:17 PM
04-30-2008, 01:51 PM
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