DCP 2.0

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  1. Quote Originally Posted by megadeth View Post
    Matt, physiologically speaking, would you know any reasons why supplements or drugs that work via PPAR-a or PPAR-y would not work on a human being? I never saw much from the original DCP. I also tried what I am pretty sure was legit gw-501516 and felt absolutely nothing. Not increase in fatloss, no stamina. Makes me wonder if the new DCP might be different for people like me or if it will be a waste of money for me. Any ideas?
    Individual expression of the PPAR isoforms varies wildly in individuals DCP 2.0 hits both alpha and delta, and includes ingredients that increase expression.
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  2. Quote Originally Posted by EasyEJL View Post
    so how do you think dcp 2.0 will work with bulk TTA on the side?
    Sounds fun.
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  3. Quote Originally Posted by Resolve View Post
    I wouldn't expect to 'feel' a PPAR agonist. Did you use another method of quantifying your results? I.e. did you not see changes in bodyfat or weight?
    Yes, I didn't see the much loss in body fat with the original DCP. When I mentioned "feel", I was referring to GW-501516. Most report a thermogenic response, increase in fat loss and increased cardiovascular endurance. I didn't experience any of this.

  4. Quote Originally Posted by megadeth View Post
    Yes, I didn't see the much loss in body fat with the original DCP. When I mentioned "feel", I was referring to GW-501516. Most report a thermogenic response, increase in fat loss and increased cardiovascular endurance. I didn't experience any of this.
    As good as it was for most not everyone responded to TTA. I'm interested to see the changes Matt makes to the formula in its absence.
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  5. Quote Originally Posted by megadeth View Post
    Yes, I didn't see the much loss in body fat with the original DCP. When I mentioned "feel", I was referring to GW-501516. Most report a thermogenic response, increase in fat loss and increased cardiovascular endurance. I didn't experience any of this.
    Gotcha, thanks for the clarification.
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  6. Just in time for the Nutra Memorial Day Sale! Woohoo

  7. Quote Originally Posted by gmc4180 View Post
    Just in time for the Nutra Memorial Day Sale! Woohoo
    Click image for larger version. 

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  8. Quote Originally Posted by gmc4180 View Post
    Just in time for the Nutra Memorial Day Sale! Woohoo
    Memorial Day...the day the fat started melting off.

  9. ][/URL]
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  10. Quote Originally Posted by dsade View Post
    ][/URL]
    Slick!
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  11. Sexy label!
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  12. Such a sexy sexy bottle.

  13. Looks great!
    EvoMuse

  14. Very nice!

  15. Ah, DCP 2.0 has me excited...can't wait for this!

  16. J Atheroscler Thromb. 2009;16(6):888-92. Epub 2009 Dec 22.
    Activating effect of momordin, extract of bitter melon (Momordica Charantia L.), on the promoter of human PPARdelta.

    Sasa M, Inoue I, Shinoda Y, Takahashi S, Seo M, Komoda T, Awata T, Katayama S.
    Source

    Department of Diabetes and Endocrinology, Saitama Medical University, Japan.

    Abstract

    AIM:

    Bitter melon (Momordica charantia L.) is a common vegetable grown in Okinawa that has also been used recently in medicine for the treatment of diseases such as diabetes, hypertension, and dyslipidemia. Among Bitter melon extracts compounds, we focused on an extract known as momordin in the present study, to examine its effect on peroxisome-proliferator activated-receptor (PPAR) delta (also called PPARdelta in rodents) expression and promoter activity of the human PPARdelta gene.
    METHODS:

    A human PPARdelta promoter-reporter plasmid was made as a template from a BAC CLONE (RPCI-11C) containing a -3076 bp (BglI site) +74 bp (EcoRI site) sequence. Luciferase assay of PPARdelta promoter activity was performed using HepG2 cells.
    RESULTS:

    10 and 25 nM Momordin significantly increased the expression of PPARdelta mRNA 1.5-fold (relative to the control). Moreover, 10 and 25 nM Momordin significantly increased PPARdelta promoter activity in a dose-dependent manner, reaching more than 1.5-fold relative to the control.
    CONCLUSION:

    Our present data obtained through successful cloning of the PPARdelta promoter demonstrate that PPARdelta production and activation are upregulated through PPARdelta promoter activity following momordin treatment.


    PMID:20032574 [PubMed - indexed for MEDLINE]
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  17. Mango, Raspberry, and now Melon! Oh my!

  18. The more I read about this product, the more impatient I get. I say we group up Ocean's 11 style and rob dsade of all his hard work.

  19. Quote Originally Posted by jwa254 View Post
    The more I read about this product, the more impatient I get. I say we group up Ocean's 11 style and rob dsade of all his hard work.
    I'm in. Who else is with us?

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  21. Well that escalated quickly.
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  22. Quote Originally Posted by metroba View Post
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    Quote Originally Posted by dsade View Post
    Well that escalated quickly.
    But does it really ever escalate slowly?

  23. Quote Originally Posted by jwa254 View Post
    But does it really ever escalate slowly?
    No, it never escalates slowly.

  24. Quote Originally Posted by jwa254 View Post
    But does it really ever escalate slowly?
    I take it you have never been on an escalator.
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  25. Quote Originally Posted by metroba View Post
    I take it you have never been on an escalator.
    I don't get on escalators. I wish I was making this up.

  26. Quote Originally Posted by jwa254 View Post
    I don't get on escalators. I wish I was making this up.
    Just think of them as drunk stairs.
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  27. I get those drunk stares all the time!

  28. Quote Originally Posted by jwa254 View Post
    I don't get on escalators. I wish I was making this up.
    Some places don't have stairs
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  29. Quote Originally Posted by metroba View Post
    Some places don't have stairs
    Then I guess I'll be staying downstairs

  30. This you?

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