Originally Posted by USPLabs

DominATP Write-Up

Following the extremely successful debut of our stimulant pre-workout product, Jack3d, we received many requests from loyal USPlabs and potential customers requesting a solid and effective non-stim pre-workout formula with proven ingredients that could be stacked with Jack3d or any other stimulant containing pre-workout formula, that could be used solo during post-afternoon training sessions, or that could even be used on resting days. In effect, you asked for a potent non-stim pre-workout blend that combines not just proven ingredients at effective doses, but that is also affordable. We went to work and are proud to present you with our response: DominATP! Composed of carefully selected proven ATP synergists, anabolic and anti-catabolic cofactors, as well as hormone-modulating agents and recovery enhancers, at effective doses, DominATP is like nothing you have experienced before.
You will feel the impact hit you after the very first dose. From that point onwards, your dominant mode will be turned on, and you will demand nothing less than crushing your workout. And with the synergistic post-exercise recovery agents included, DominATP makes you look forward to your next workout! Every time! Your personal experience is your best feedback!

DominATP delivers:

• Powerful triggering and modulation of protein synthesis and reduction of muscle degradation via proven synergistic anabolic and anti-catabolic agents
• Significant boost in phosphocreatine synthesis, ATP regeneration, and VO2 max, for heightened strength and endurance
• Dramatic improvements in muscular integrity, muscle contractions, and muscular capacity
• Radical preferential stimulation of fast-twitch muscle fibers for explosiveness and power
• Boost in mitochondrial respiration, oxygen utilization, aerobic and anaerobic capacity
• Dramatically postponed onset of muscle fatigue and muscle failure
• Enhanced secretion of growth hormone, luteinizing hormone, and follicle-stimulating hormone
• Improved insulin response
• Elevated endothelial nitric-oxide synthesis, vasodilation, and muscle fullness
• Powerful antioxidant, anti-inflammatory, immune, and anti-aging support

The ingredients:

DiCreatine Malate Creatine (methyl guanidine-acetic acid, or
N-(Aminoiminomethyl)--N-methylglycine) is a naturally occurring metabolite found in red muscle tissue. Creatine can be obtained from endogenous synthesis, from diet, and from supplementation. Endogenously, creatine is metabolized in the liver from the amino acids glycine, arginine, and methionine. It is then released into the blood stream to be absorbed into muscle cells. It can also be produced in small amounts by the kidney and pancreas, in exceptional cases. As the body is unable to synthesize adequate amounts of creatine and creatine phosphate
(phosphocreatine) during times of high-intensity exertion, creatine supplementation becomes crucial. It has a substantially well established status as a strength and endurance booster (via its role in adenosine triphosphate (ATP) synthesis), a cellular hydrating agent (or cell volumizer), an important lactic acid buffer, a body mass enhancer, as well as a post-exercise recovery agent. As it turns out, some users of standard creatine monohydrate experience bloats and gastro-intestinal problems. Bonding creatine to malic acid appears to solve these problems, while providing users with the accustomed benefits of creatine supplementation. In particular, DiCreatine Malate is a molecular bonding of creatine to malate, the salt form of malic acid, in an approximately
2:1 ratio that effectively supplies the body with adequate amounts of creatine, creatine phosphate and ATP.

Traditionally, malate has been molecularly bonded to minerals, amino acids, and vitamins to improve their stability, their absorbability, as well as their bioactivity. The same principle was realized in dicreatine malate, making this advanced creatine form more PH-stable, more soluble, and significantly more bioavalable than standard creatine monohydrate.
Furthermore, as a Krebs Cycle intermediate, malate not only acts as an effective carrier for creatine, but also directly supports the production of ATP, leading to improved VO2 max and energy metabolism in skeletal muscle cells and heart myocytes. Consequently, dicreatine malate offers a unique and synergistic fusion of ATP-promoting agents, creating a powerful compound for enhancing endurance, strength, and recovery.

The malate bond is significant for another reason. Malic acid is the only Krebs Cycle metabolite that is depleted during times of physical exertion, and is one of the first steps toward physical exhaustion. As a consequence, replenishing malic acid levels via dicreatine malate supplementation plays an incredibly significant role in ATP resynthesis and energy production. As we will see later, malic acid is also involved in important detoxification processes in the body, thereby ensuring more intense workouts, delayed fatigue and muscle failure, and optimal recovery.


Beta-Alanine
This compound needs little introduction. As is well known, Beta-Alanine (the only naturally occurring ß-amino acid) and L-Histidine form the bedrock for the synthesis of the compound L-Carnosine, a very powerful pluripotent dipeptide intricately involved in a variety of deep metabolic processes. Upon consumption or supplementation in sufficient quantities, carnosine is metabolized by the enzyme carnosinase into its precursor amino acids, beta alanine and l-histidine. After absorption into skeletal muscle cells, another enzyme, carnosine synthase resynthesizes carnosine into its constituents, beta alanine and l-histidine.

Why is this of any significance to athletes? First, so-called long-lived cells, for example, nerve cells (neurons) and muscle cells (myocytes) are known to contain high concentrations of carnosine, with the level of carnosine positively correlating with the capacity for high-intensity exercise performance as well as the maximum life spans of animal species. Now, let us take a quick look at muscle fibers. There are two broad types of muscle fibers in humans, Type I
(slow-twitch) with a limited growth capacity, and Type II (fast-twitch) with a high potential capacity for growth. Type I muscle fibers appear to be more prevalent. Although carnosine is also found in Type I muscle fibers, it is preferentially located in Type II muscle fibers responsible for explosiveness and power. This means that by deliberately increasing our cellular carnosine concentrations via supplementation, we can preferentially induce higher carnosine loads in Type II muscle fibers, thus stimulating their growth and our overall muscular capacity.

Furthermore, as is well known, high intensity exercise induces a rise in intracellular H+ (hydrogen ions) and lactic acid levels, signalling the onset of fatigue, muscle failure, and reduced performance. In this connection, carnosine not only acts as a powerful antioxidant in skeletal muscle cells, but also functions as a key pH buffer, inducing the neutralization of lactic acid, and protecting skeletal muscle cell membranes from oxidation within the acidic conditions of muscular exertion. These translate into delayed fatigue and enhanced performance, as well as improved muscular integrity and contractions (due to the activation of myofibrillar-ATPase enzymes responsible for muscle contractions), with carnosine supplementation. Relatedly, carnosine also supports more efficient heart-muscle contractions via the improvement of calcium response (high acidic levels reduce ATP efficiency and obstructs calcium release) in heart myocytes, leading to improved endurance.
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