PROLACTRONE FAQ***

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    PROLACTRONE FAQ***


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    Prolactrone reduces prolactin levels and significantly increases Growth hormone levels.
    In this study you will see that Ldopa administered concurrent with a decarboxylase inhibitor increases growth hormone levels.
    The level of increase seen in this study was comparable to 5-7 IU injected growth hormone.

    Eur J Pediatr. 1976 Jun 8;122(3):195-200.
    [HGH secretion after oral application of L-dopa and L-carbidopa (author's transl)].
    [Article in German]
    Sch?nberger W, Ziegler R, Brodt B, Grimm W.
    Abstract

    The stimulatory effect of L-Dopa and L-Carbidopa (Nacom) on HGH secretion was determined in 12 children of normal height aged from 6 to 14 years. Each child received a standard dose of 250 mg L-Dopa and 25 mg L-Carbidopa p.o. HGH concentration in the serum was determined at standard intervals. All subjects showed a sufficient increase of HGH. The mean value was 19.6 ng/ml. According to the maximum values of the HGH concentration the sample can be divided into two groups; the first group reached the highest values after 20--40 min, the second one after 60--90 min. On evaluation of the curve of the mean values it appears that 2 blood samples taken 40 and 90 min after the ingestion of L-Dopa and L-Carbidopa are sufficient in order to exclude HGH deficiency. The theoretical background for HGH secretion after stimulation by L-Dopa and L-Carbidopa is discussed.

    PMID:
    1278188
    [PubMed - indexed for MEDLINE]

    [HGH secretion after oral application of L-dop... [Eur J Pediatr. 1976] - PubMed - NCBI
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    In this study we see Ldopa administered concurrent with a decarboxylase inhibitor decreased Prolactin levels.
    It also shows that in order for Ldopa to effectively reduce prolactin metabolism MUST happen in the brain.
    This means that other supplements currently available which claim to inhibit prolactin DO NOT WORK.

    Why? Because they contain vitb6 or P5P which increases metabolism outside the blood brain barrier rendering the supplement inactive.
    In contrast, Prolactrone contains a strong decarboxylase inhibitor which prevents metabolism outside the blood brain barrier making Prolactrone the ONLY effective prolactin reducing supplement on the market...period.

    Highlight 1. Ldopa suppresses prolactin.
    2. The addition of carbidopa (a decarboxylase inhibitor similar to that which is in Prolactrone) further enhances the prolactin reducing effect.
    3. Ldopa acts predominantly through the formation of dopamine in the hypothalamus, but inside the blood-brain barrier which requires the concurrent administration of a decarboxylase inhibitor.

    Neurology. 1981 Oct;31(10):1356-9.
    Prolactin secretion in Parkinson disease.
    Eisler T, Thorner MO, MacLeod RM, Kaiser DL, Calne DB.
    Abstract

    We studied the dopaminergic control of lactotroph cells in the anterior pituitary of parkinsonian patients and age-matched normal subjects. The resting levels of prolactin and the TRH-induced rise in prolactin were normal in Parkinson disease. 1. --Levodopa elicited a normal suppression of prolactin concentrations in parkinsonian subjects; the major abnormality to emerge was attenuation of the response to thyrotropin-releasing hormone (TRH) in the parkinsonian patients following administration of Sinemet (levodopa plus carbidopa) or bromocriptine. These findings imply pathology of extrastriatal dopamine systems in Parkinson disease. 2. Since the addition of carbidopa enhanced the suppression of prolactin induced by levodopa, exogenous levodopa probably 3. acts predominantly through the formation of dopamine in the hypothalamus, but inside the blood-brain barrier, rather than as a direct effect of circulating dopamine on the anterior pituitary or areas of the hypothalamus outside the blood-brain barrier.

    PMID:
    6810204
    [PubMed - indexed for MEDLINE]

    http://www.ncbi.nlm.nih.gov/pubmed/6810204
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    Here is bloodwork.
    User was at week 8. 400mg trenbolone per week.
    1 capsule Prolactone daily.
    Attached Images Attached Images  
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    Really! All that from pill? I like it for the GH level aspect of it....
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    Quote Originally Posted by usealittle
    Really! All that from pill? I like it for the GH level aspect of it....
    Weird to see products that work right?

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    so should i take one before bed?
    im currently stacking REM PM + ups powerFULL
    if that works i could add prolactrone
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    USP Powerfull contains velvet bean which is what LDOPA is extracted from.
    It doesnt say what % so you actually dont know how much your taking, however, since Prolactrone has alot of 99% LDOPA you probably dont want to mix them.
    Prolactrone contains LDOPA plus an additional ingredient to make it work better so....Prolactrone > USP Powerfull.
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    i read somewhere that 1g of Ldopa is the sweet spot for the drug. but you dont want to over due it with Ldopa.... most drugs you can but not with Ldopa.
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    Yah for sure under 1 gram. We keep it at about half that for the top end dose.
    Around 1g side effects begin to outweigh positive effects.
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    Quote Originally Posted by brundel View Post
    Here is bloodwork.
    User was at week 8. 400mg trenbolone per week.
    1 capsule Prolactone daily.
    I'm a little confused at how you can conclude any effects on this indiv. without any pre-cycle blood work to compare???

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