Originally Posted by kevinhy
I have a theory that DAA might be useful during a PH cycle, but its just speculation.
DAA works by stimulating the NMDA receptors in the hypothalamus, which increases concentrations of GnRH (Gonadotropin-releasing hormone). GnRH then stimulates the pituitary to increase concentrations of both LH (Luteinizing hormone) and FSH (Follicle-stimulating hormone), which tells the testes to turn on the testosterone making process (Steroidogenesis).
When you take PH/DS/AAS, these very same pathways are down-regulated (reduced LH, FSH, etc). In theory, if one were to co-administer both exogenous androgens and DAA, it seems possible that they would neutralize each other, potentially minimizing (or slowing) the shutdown process that the PHs cause.
Adamantium also increases androgen receptor density in muscle cells, which would increase the effectiveness of the PHs you're using. Whether or not the DAA is strong enough to counteract the negative feedback caused by PH/DS is definitely not known, so just use this as food for thought. I think it seems plausible at best though, mainly depending on what products you intend on using.