RPM FAQs

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    RPM FAQs


    Here you go!!!!!

    RPM™ from Applied Nutriceuticals™
    Frequently Asked Questions






    Q: How long will it take to feel the positive benefits of RPM?

    A: You will feel the many of the benefits of RPM within 1 hour of taking the first dose. Users frequently report new personal records (PRs) on all major exercises within the first week of starting RPM. Users of RPM report intense focus, heightened aggression towards training and an overall “hardening” effect, along with strong vasodilation and intense pumps. The “focus-enhancement” properties of RPM also manifest themselves on the first dose, while the full effects of the testosterone- boosting and the anti-estrogenic actions of RPM become evident after 2-3 doses. This accomplishes one of our primary product development goals; to develop a completely new product that provides immediate results while continually working better over time.

    Q: What are the ingredients of RPM?

    A: P-SARM Synthase AI
    Icariin 50% Extract (research-grade)
    Grape Seed Extract (specially extracted fir 98% Oligometric Proanthocyanidins)
    L-Arginine Base
    Naringin (98% Citrus Flavanoids extracted for Naringenin)

    Methyl AMP Complex
    Chocamine
    Methyl Xanthine Anhydrous Caffeine


    Q: How is RPM different from other testosterone boosters and NO-type products?

    A: RPM resides in a completely new product category of its own: It is an A-CESE (Anabolic-Cognitive Energy System Enhancer) with P-SARM (Phytochemical Selective Androgen Receptor Modulator) characteristics. This means that the product that exhibits testosterone-mimetic, anti-catabolic, and aromatase-inhibiting properties, while at the same time delivers optimal mind/muscle connection & contraction. This is accomplished through its unique peripheral vasostimulatory perfusion and increased cognitive psycho-motor control.

    RPM combines P-SARM Synthase AI- a unique blend of research-grade icariin (high-quality research grade icariin, 50% extract), L-Arginine, and the flavanoid aromatase inhibitors naringin (specially standardized for naringenin), and grape seed extract (specially standardized for oligomeric proanthocyanidins (OPCs), along with Methyl-AMP Complex, a powerful blend of methyl-xanthine caffeine and Chocamine™, standardized in a specific ratio to ensure for maximum vasodilatory properties and mind/muscle psycho-motor connection.


    Q: Does RPM require post cycle therapy? (special thanks to TheMyth on this one!!!!)

    A: RPM does NOT require post cycle therapy b/c it works through secondary characteristics (AI effect, effects on SHBG, effects on T:E and T:C ratio)- this maximizes free endogenous T, while minimizing estrogen and cortisol- HPTA shutdown only occurs when exogenous testosterone derivatives are introduced.

    Q: When should I take RPM?

    A: Take approximately one hour before your workout. If you train in the evening, do not take a full dose within 6 or 7 hours of bedtime. If you do train in the evening, reduce you recommended dosage by 50%.

    Q: Has there been any scientific research on the product constituents of RPM?

    A: Absolutely. The components in RPM all have numerous medical research studies proving their efficacy, with documented properties including testosterone enhancement, anti-catabolism, and a PDE5 inhibition with mechanisms of action similar to Viagra. All the product constituents of both P-SARM Synthase AI and the Methyl-AMP Complex have been studied extensively, and only the doses and standardizations used in research studies are used in the product. Full references are sited at the conclusion of RPM’s technical write-up, which can be found at www.appnut.com.

    Q: I thought all research on SARMs (selective androgen receptor modulators) was limited to potential pharmaceutical drugs?

    A: To be considered a SARM (selective androgen receptor modulator), a compound must have the following characteristics:
    • Stimulate increases in strength and fat-free mass through testosterone mimetic properties,
    • Support bone growth
    • Maintain and / or restore sexual function and virility
    • Orally bioavaliable
    • Does not effect blood pressure or blood lipids.
    RPM fits every one of these criteria for a SARM. The only exception is that it is a compilation of phytochemical extracts rather than a pharmaceutical-grade preparation - hence the classification of Phytochemical SARM (P-SARM). RPM is very well researched and all components have undergone extensive testing on humans and animals; as opposed to the alternative - which is an unproven pharmaceutical drug that so far has only been tested on animals.


    Q: Is it safe to use RPM for long periods of time, or should I cycle it?

    A: All research studies along with our own testing have indicated that it can be used continuously without any negative side effects- some members of the AN team have used various components of RPM for a year straight, with no issues. You will never want to train without it again!

    Q: What supplements should I take along with RPM, and are there any supplements I should avoid?

    A: We recommend whey protein supplementation, with a goal of attaining 1-1.5 grams of protein per day per lb. of bodyweight. Additionally we encourage the use of an EFA supplement with a proper ratio of omega 3/6/9, and a good multivitamin / multimineral. IGF-2 and NeoVar stack extremely well with this compound as well! Please drink at least 70 oz. of water a day while taking RPM as well.

    Please avoid any other stimulant or thermogenic while taking RPM- you simply will not need them! RPM is a strong thermogenic, on par with ephedra products- try it and see for yourself! Plus, now you can save money since you won’t need a separate stimulant-based fat-burning product!

    Q: Who can benefit from RPM?

    A: Anyone seeking to DRIVE their workouts to an explosive, vein-popping new level. The product is also a great contest-prep item, giving the user tighter skin, less water retention, harder muscle contractions, and bulging pumps, even on limited carbs!! Also, anyone looking to gain a competitive edge in athletics can benefit significantly from using RPM, from both the strength increases and the heightened concentration and focus; plus it is NCAA, NPC, IFBB, NFL, NBA, MLB and IOC compliant!

    Q: Who should not take RPM?

    A: Anyone sensitive to stimulants, under the age of 18, those who take MAOI’s or are on any other type of prescription medications, and if you are pregnant or nursing. Always check with your doctor before beginning any supplementation regimen.
    Dirk Tanis, BA, MSci
    Chief Operating Officer, Applied Nutriceuticals

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    Looks good! I'm finally gonna get to try my sample today!!

    ps. You might want to change the part where you define SARMs from "reuptake" to "receptor".
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    Quote Originally Posted by rpen22 View Post
    Looks good! I'm finally gonna get to try my sample today!!

    ps. You might want to change the part where you define SARMs from "reuptake" to "receptor".
    Good catch-fixed!!
    Dirk Tanis, BA, MSci
    Chief Operating Officer, Applied Nutriceuticals
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    Very nice post!


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    Awesome

    One more question. This mentions being having thermogenic properties, should I avoid it while bulking?

    I was thinking to use it to make my clean bulk, "more clean."

    LOL I think I'm gonna use this on my bulk anyway HAHA

    Should help with some recomp stuff too at the same time
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    Quote Originally Posted by icey View Post
    Awesome

    One more question. This mentions being having thermogenic properties, should I avoid it while bulking?

    I was thinking to use it to make my clean bulk, "more clean."

    LOL I think I'm gonna use this on my bulk anyway HAHA

    Should help with some recomp stuff too at the same time
    RPM will make an awesome addition on a bulk, and yes, it will go a long way in helping you make and achieve clean lean mass gains without the excess bagagge.
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    The Anti-E effects are awesome to keep down any extra bloat as well..... makes you look and feel much harder.
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    Just got back from my first workout with my RPM sample.

    This stuff is TIGHT.
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    The man said Tight..... I'm about to rep you.
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    Tizzight !

    lol

    Well I'm gonna place an order for a couple of bottles soon as this thing is ready

    Thanks guys great work looking forward to it.
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    Quote Originally Posted by icey View Post
    Awesome

    One more question. This mentions being having thermogenic properties, should I avoid it while bulking?

    I was thinking to use it to make my clean bulk, "more clean."

    LOL I think I'm gonna use this on my bulk anyway HAHA

    Should help with some recomp stuff too at the same time
    Very good question! Yes, it would make a clean bulk more "clean" by adding in a very pronounced thermogenic response- however, the appetite suppression factor on RPM is VERY mild- once the stim part wears off, you become ravenously hungry!!

    The non-stim product will more than likely make your appetite SKYROCKET, but the product constituents will still allow for a thermogenic effect, even w/o stims- a re-comper's dream!!
    Dirk Tanis, BA, MSci
    Chief Operating Officer, Applied Nutriceuticals
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    Quote Originally Posted by icey View Post
    Tizzight !

    lol

    Well I'm gonna place an order for a couple of bottles soon as this thing is ready

    Thanks guys great work looking forward to it.
    Keep us posted on your results!!
    Dirk Tanis, BA, MSci
    Chief Operating Officer, Applied Nutriceuticals
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    ALSO- if there are any other questions that you think are relevant to the FAQ, and you would like to know the answer to, post them UP!!!

    Your feedback is helping me write this thang!!!
    Dirk Tanis, BA, MSci
    Chief Operating Officer, Applied Nutriceuticals
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    Quote Originally Posted by rms80 View Post
    ALSO- if there are any other questions that you think are relevant to the FAQ, and you would like to know the answer to, post them UP!!!

    Your feedback is helping me write this thang!!!
    Rms80,

    The question Iíve run into from a couple of people goes something like this, ďIf it mimics testosterone, then will it shut down your own hormones? And if it doesnít shut you down, then why doesnít it?

    Iíve been spreading the word for you guys in my workout place.

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    check the FAQ's, he just updated it.
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    Quote Originally Posted by tuberman View Post
    Rms80,

    The question Iíve run into from a couple of people goes something like this, ďIf it mimics testosterone, then will it shut down your own hormones? And if it doesnít shut you down, then why doesnít it?

    Iíve been spreading the word for you guys in my workout place.

    Thanks bro!!! Yeah- TM asked the same question as you, so I added the answer into the FAQs....
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    Can RPM be stacked with powerfull? also, im taking novedex xt at night. can i still take rpm?
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    Quote Originally Posted by metroba View Post
    Can RPM be stacked with powerfull? also, im taking novedex xt at night. can i still take rpm?
    Yeah, those three will work together. Powerfull appears to be a combo of mucuna pruriens (l-dopa) and safed musli, so it's kinda like a lesser version of IGF-2. The novedex, being an AI, may create too much estrogen suppression with the AI effects of RPM... if this occurs, then try lowering the Novedex dose just a bit. You can tell if estrogen is being too far suppressed by certain symptoms such as sore joints and dry skin.
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    Quote Originally Posted by Aeternitatis View Post
    Yeah, those three will work together. Powerfull appears to be a combo of mucuna pruriens (l-dopa) and safed musli, so it's kinda like a lesser version of IGF-2. The novedex, being an AI, may create too much estrogen suppression with the AI effects of RPM... if this occurs, then try lowering the Novedex dose just a bit. You can tell if estrogen is being too far suppressed by certain symptoms such as sore joints and dry skin.
    Thanks for the advice. I am currently doing 3 caps at night of the novedex. next week it will be 2 caps for 2 weeks and then 1 cap for 2 weeks. rpm looks awesome cant wait to try it!! looking forward to reading some logs on it.
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    Quote Originally Posted by Aeternitatis View Post
    Yeah, those three will work together. Powerfull appears to be a combo of mucuna pruriens (l-dopa) and safed musli, so it's kinda like a lesser version of IGF-2. The novedex, being an AI, may create too much estrogen suppression with the AI effects of RPM... if this occurs, then try lowering the Novedex dose just a bit. You can tell if estrogen is being too far suppressed by certain symptoms such as sore joints and dry skin.
    Good call- I think AI action of the Novadex may dry your joints out even further (RPM seems to get them pretty dry through the AI/anti-catabolic effect)- might be overkill- but I agree with Aeternitatis, should be a good combo...

    I have noticed slightly more brittle joints and much "drier" look since starting RPM- it was noticeable after a few days...
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    • Support bone growth
    Can someone expound on this?
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    Quote Originally Posted by poison View Post
    Can someone expound on this?
    Sure!!! Icariin has some osteogenic enhancing anti-catabolic activities- this is also a characteristic of all SARMs and anabolic steroids.......

    Icariin actually shares many of the tendon, joint, and bone enhancing qualities of cissus quadrangularis, and has been studied even more extensively than cissus over the last few years in this regard


    Phytomedicine. 2007 May 3; [Epub ahead of print]
    Effects of total flavonoids and flavonol glycosides from Epimedium koreanum Nakai on the proliferation and differentiation of primary osteoblasts.

    * Zhang DW,
    * Cheng Y,
    * Wang NL,
    * Zhang JC,
    * Yang MS,
    * Yao XS.

    Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, PR China; Shenzhen Research Institute of City University of Hong Kong, Shenzhen 518057, PR China.

    In a bioassay-guided drug screening for anti-osteoporosis activity, eight flavonol glycosides were isolated from Epimedium koreanum Nakai, which is traditionally widely used in China for the treatment of impotence and osteoporosis. The effects of total flavonoids and flavonol glycosides on the proliferation and differentiation of rat calvarial osteoblast-like cells were evaluated by the MTT method and measuring the activity of alkaline phosphatase (ALP activity). Total flavonoids (1.2 x10(-2) to 6.0 x10(-7) mg/ml) and flavonol glycosides (2.0 x10(-5) to 1.0 x10(-9) mol/l) exhibited a strong inhibition on the proliferation of primary osteoblasts at most concentrations. However, the total flavonoids and icariin significantly promoted the differentiation of primary osteoblasts. The results suggested that flavonoids from E. koreanum Nakai may improve the development of osteoblasts by promoting the ALP activity; and icariin might be one of the active constituents facilitating the differentiation of osteoblasts.



    Chin Med J (Engl). 2007 Feb 5;120(3):204-10.Click here to read Links
    Icariine stimulates proliferation and differentiation of human osteoblasts by increasing production of bone morphogenetic protein 2.

    * Yin XX,
    * Chen ZQ,
    * Liu ZJ,
    * Ma QJ,
    * Dang GT.

    Department of Orthopaedics, Peking University Third Hospital, Beijing, 100083, China.

    BACKGROUND: Icariine is a flavonoid isolated from a traditional Chinese medicine Epimedium pubescens and is the main active compound of it. Recently, Epimedium pubescens was found to have a therapeutic effect on osteoporosis. But the mechanism is unclear. The aim of the study was to research the effect of Icariine on the proliferation and differentiation of human osteoblasts. METHODS: Human osteoblasts were obtained by inducing human marrow mesenchymal stem cells (hMSCs) directionally and were cultured in the presence of various concentrations of Icariine. 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) test was used to observe the effect of Icariine on cell proliferation. The activity of alkaline phosphatase (ALP) and the amount of calcified nodules were assayed to observe the effect on cell differentiation. The expression of bone morphogenetic protein 2 (BMP-2) mRNA was detected by reverse transcriptase-polymerase chain reaction (RT-PCR). RESULTS: Icariine (20 microg/ml) increased significantly the proliferation of human osteoblasts. And, Icariine (10 microg/ml and 20 microg/ml) increased the activity of ALP and the amount of calcified nodules of human osteoblasts significantly (P < 0.05). BMP-2 mRNA synthesis was elevated significantly in response to Icariine (20 microg/ml). CONCLUSIONS: Icariine has a direct stimulatory effect on the proliferation and differentiation of cultured human osteoblast cells in vitro, which may be mediated by increasing production of BMP-2 in osteoblasts.

    Zhong Yao Cai. 2006 Oct;29(10):1062-5. Links
    [The effect of icariin and astragalosid I on the proliferation and differentiation of bone marrow stromal cells]
    [Article in Chinese]

    * Liu HJ,
    * Wang XP,
    * Lin J,
    * Yu YC,
    * Jiang XQ,
    * Zhang XL,
    * Zhou ZT,
    * Zhang WD.

    The College of Stomatology, Tongji University, Shanghai 200072, China.

    OBJECTIVE: To observe the effects of icariin and astragalosid I on the proliferative and alkaline phosphatase (ALP) activity of dog bone marrow stromal cells (BMSCs). METHODS: The dog's BMSCs were isolated and cultured in vitro. The 3th generation BMSCs were treated with icariin or astragalosid I at the concentration of 50 ng/ml and compared with BMSCs of BMP-2 group and control group. The growth curves of BMSCs were drawn by 3-(4,5-dimiethylthiazole-2-yl)-2, 5-hiphenyl tetrazolium bromide (MTT) colorimetric assay every day from the 1st to the 8th day to estimate the proliferative ability of BMSCs. The curves of OD value of ALP excreted by BMSCs on the 1st, 3th, 6th, 10th and the 14th day were recorded to estimate the ALP activity of BMSCs. RESULTS: After the pertreatment with icariin and astragalosid I, the BMSCs acquired higher MTF values and higher ALP's OD values as compared with control group and the difference between experiment group and control group was statistically significant (P < 0.05). CONCLUSION: Icariin and Astragealosid I can accelerate the proliferation and ALP excretion of BMSCs. At the same time, the osteogenesis ability of these cells is greatly improved.

    J Huazhong Univ Sci Technolog Med Sci. 2005;25(6):690-2.
    Effects of Icariin on expression of OPN mRNA and type I collagen in rat osteoblasts in vitro.

    * Xiao Q,
    * Chen A,
    * Guo F.

    Department of orthopaedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

    To study the effects of Icariin on expression of osteopontin (OPN) mRNA and type I collagen in rat osteoblasts in vitro and to explore its possible mechanisms in preventing osteoporosis. OB was isolated from calvaria of new-born new-born fetal Sprague-Dawley (superdrol) rats by means of modified sequential collagenase digestion and incubated in MEM medium and the cell morphology was observed under inverted phase contrast microscope, OB was identified by alkaline phosphatase (ALP) staining. Different concentration (0.1 microg/mL, 1.0 microg/ml, 10 microg/mL) of Icariin was added to the OB and incubated. The effect of Icariin on the proliferation and osteogenesis of OB was monitored by MTT analysis. The expression of type I collagen was estimated with immunohistochemistry techniques. The expression levels of mRNA of OPN in the cells in every group were examined by reverse-transcriptase ploymerase chain reaction (RT-PCR). The expression of OPN mRNA and type I collagen was strengthened gradually with the increase of Icariin concentration and peaked with 10 microg/mL Icariin on the 5th day. Icariin could significantly promote the expression of OPN mRNA and type I collagen in rat osteoblasts in vitro. The levels of expression of OPN mRNA and type I collagen were changed with different concentration of Icariin. Icariin could effectively prevent and treat osteoporosis and promote the bone formation.



    Pharmazie. 2005 Dec;60(12):939-42. Links
    Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells.

    * Chen KM,
    * Ge BF,
    * Ma HP,
    * Liu XY,
    * Bai MH,
    * Wang Y.

    Institute of Orthopaedics, Lanzhou General Hospital, Lanzhou, Gansu 730050, PR China. Chkeming@yahoo.com.cn

    The herb Epimedium has long been used in Traditional Chinese Medicine to treat bone fracture and prevent osteoporosis. Researchers believe that the flavonoids contained in the herb are the effective component for this activity. However, no single flavonoid has been studied for its effect on bone-related cells. In the present study, icariin, one of the major flavonoids of the herb, supplemented the primary culture medium of rat bone marrow stromal cells (rMSCs) at 0.1 microM , 1 microM and 10 microM respectively. It was found that icariin stimulated the proliferation of rMSCs and increased the number of CFU-F stained positive for alkaline phosphatase in a dose-dependent manner. Icariin also dose-dependently increased the alkaline phosphatase activity, osteoalcin secretion and calcium deposition level of rMSCs during osteogenic induction. The addition of 10 microM icariin caused four times more mineralized bone nodules to be formed by rMSCs than in the control. The results demonstrated that icariin should be an effective component for bone-strengthening activity, and one of the mechanisms is to stimulate the proliferation and enhance the osteogenic differentiation of MSCs.



    Wei Sheng Yan Jiu. 2005 Mar;34(2):191-3. Links
    [Effects of Icariin on ovariectomized osteoporotic rats]
    [Article in Chinese]

    * Bao JR,
    * Yang JW,
    * Li SF,
    * Zhao W,
    * Zhang Q,
    * Yan Y.

    Life Science College, Northeast Agricultural University, Harbin 150030, China.

    OBJECTIVE: To observe the effects of Icariin on ovariectomized osteoporotic rats. METHODS: Female Wistar rats were ovariectomized and administered different dosage of Icariin and 17beta-estradiol for eight weeks. Bone mineral density (BMD), indexes of biomechanics and bone metabolism-associated biochemical markers were measured. RESULTS: Icariin increased the BMD, maximum load and flexural rigidity in the osteoporotic rats. The activities of serum tartrate-resistant acid phosphatase (TRACP) and bone alkaline phosphatase (BALP) were decreased in the Icraiin-fed ovariectomized rats. CONCLUSION: Icariin 225mg/kg per day could increase the BMD and improve indexes of bone biomechanics in ovariectomized osteoporotic rats. It was effective in preventing bone loss induced by ovariectomy.



    Zhongguo Zhong Yao Za Zhi. 2005 Feb;30(4):289-91. Links
    [Effects of Epimedium pubescens icariine on proliferation and differentiation of human osteoblasts]
    [Article in Chinese]

    * Yin XX,
    * Chen ZQ,
    * Dang GT,
    * Ma QJ,
    * Liu ZJ.

    Third Hospital of Peking University, Beijing 100083, China. yxx2733_cn@sina.com

    OBJECTIVE: To study the effects of epimedium pubescens icariine on the proliferation and differentiation of human osteoblasts. METHOD: Human osteoblasts were obtained by inducting human marrow mesenchymal stem cells (hMSCs) directionally. MTT was used to observe the proliferation and activity of ALP was assayed to observe the differentiation of the third passage human osteoblasts cultured in vitro. The expression of BMP-2 mRNA was checked by RT-PCR. RESULT: Epimedium pubescens icariine at the dose of 20 microg x mL(-1) increased greatly the proliferation and differentiation of human osteoblasts and promoted the expression of BMP-2 mRNA. CONCLUSION: Epimedium pubescens icariine enhances significantly the proliferation and differentiation of human osteoblasts, which may be mediated by increasing the expression of BMP-2 mRNA.
    Dirk Tanis, BA, MSci
    Chief Operating Officer, Applied Nutriceuticals
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    If that post were a kung fu master it'd be like:

    :bruce1:

    You guys continue to blow my mind.
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    Quote Originally Posted by Aeternitatis View Post
    If that post were a kung fu master it'd be like:

    :bruce1:

    You guys continue to blow my mind.
    Just trying to keep everyone educated!!
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    CANT HELP BUT READ THIS OVER AND OVER AGAIN!!!!

    Great Job D!!!
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    Holy crap! Fantastic stuff, thank you so much!
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    Man I love my sample buying some for sure! release date? I took some before work and I was flying off the wall.
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    Quote Originally Posted by TiTanUp View Post
    Man I love my sample buying some for sure! release date? I took some before work and I was flying off the wall.
    Good to Hear TiTan There is some INFO coming!! not much longer!!
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    What about a stack like this:

    1) PowerFULL
    2) IGF-2
    3) RPM

    Do you guys think that is overkill? PowerFULL and IGF-2 seem like they are trying to accomplish the same goal. Right now I'm using PowerFULL but I noticed IGF-2 is recommended to be cycled so I need to find out if PowerFULL should be cycled as well cause I might just do it like this:

    1) PowerFULL/RPM weeks 1-8
    2) IGF-2/RPM weeks 9-16

    What do you guys think? I know you can't comment on PowerFULL in terms of dosing/cycling since that's not your company but was just curious if people had been trying them together.

    Thanks,

    Ice
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    yay it got stickied


    thank you admin
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    Quote Originally Posted by Outside Backer View Post
    yay it got stickied


    thank you admin
    Thanks Joe!!!!
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    Quote Originally Posted by icey View Post
    What about a stack like this:

    1) PowerFULL
    2) IGF-2
    3) RPM

    Do you guys think that is overkill? PowerFULL and IGF-2 seem like they are trying to accomplish the same goal. Right now I'm using PowerFULL but I noticed IGF-2 is recommended to be cycled so I need to find out if PowerFULL should be cycled as well cause I might just do it like this:

    1) PowerFULL/RPM weeks 1-8
    2) IGF-2/RPM weeks 9-16

    What do you guys think? I know you can't comment on PowerFULL in terms of dosing/cycling since that's not your company but was just curious if people had been trying them together.

    Thanks,

    Ice
    Any thoughts on this guys? I know you are all busy and stuff with the release coming
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    Quote Originally Posted by icey View Post
    Any thoughts on this guys? I know you are all busy and stuff with the release coming
    I'd call it redundant. If you want more power out if it either slightly increase the IGF-2 dosage or add some Lipotrophin-PM.
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    Quote Originally Posted by Aeternitatis View Post
    I'd call it redundant. If you want more power out if it either slightly increase the IGF-2 dosage or add some Lipotrophin-PM.

    Cool thanks for the advice
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    How about other stack suggestions?

    Like:

    RPM/Mass Fx (with or without Hyperdrol/HD X2)
    RPM/Bad Ass Mass (with or without Jungle Warfare)

    Or RPM with an androgen.

    Like: (my favorite)

    RPM/Epistane
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    The latter looks promising.


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    RPM and Epistane? It doesn't really make sense to stack a natural T booster with something that suppresses T. Further, epistane already has AI properties, why would you want to suppress estrogen further while on-cycle? Sounds like a bad stack to me.

    RPM with ActivaTe would be better than with BAM or MassFX, IMO. I'm not too hot on supplements that don't try to offer evidence for how or why they work. Right now, I'm assuming the main ingredients in BAM and MFX work similarly to the principle actives in safed musli (which can be found in IGF-2)
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    Quote Originally Posted by Aeternitatis View Post
    RPM and Epistane? It doesn't really make sense to stack a natural T booster with something that suppresses T. Further, epistane already has AI properties, why would you want to suppress estrogen further while on-cycle? Sounds like a bad stack to me.
    Don't know, ask the man in charge...

    Quote Originally Posted by rms80 View Post
    Yeah!!! There should be some awesome synergism going on, b/c from what we do know, the components of RPM do the following:
    -RPM acts as an AI, inhibiting SHBG, and raising free testosterone levels
    -AIs alter the Test:estrogen ratio, also raising free test levels
    -Icariin has a PDE5 inhibiting effect, which causes vasodilation and the extreme "pump" that users report
    -PDE5 inhibitors have been shown to positively skew the test:cortisol ratio, upping free testosterone levels
    -Icariin has been shown to block the binding of cortisol to receptor sites, upping the T:C ratio

    Now put all this together in time-dependant medium- you have high free testosterone levels, low estrogen, low shbg, and very little binding of cortisol- this is a VERY anabolic state- especially b/c most of these effects occur almost IMMEDIATELY (within the first 3 doses) with RPM!!!!

    My guess is that Epi and RPM will be a PHENOMENAL stack for hardness, vascularity and strength, b/c from what we do know, epi has a STRONG affinity for the AR- so basically you would have a compound (RPM) that is extremely effective in boosting testosterone through both (less prevalent) primary and secondary (more prevalent) mechanisms, and another compound (Epi) that does the exact same thing, except in reverse- Epi primarily acts through direct AR-binding, and to a lesser extent through secondary mechanisms (it does inhibit SHBG). This is a textbook stack right here- the users takes two compounds and maximizes both primary and secondary characteristics, thus enhancing synergy between the two said compounds!!!!!
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    Well, RPM would have some benefit, but it seems to me that most would be negated by the natural T shutdown. IDK, maybe I misunderstand how epi works.

    I could definitely see RPM in use during PCT for epi though.
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