IGF-2™ Frequently Asked Questions

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    IGF-2™ Frequently Asked Questions


    Q: When is the best time to take IGF-2?

    A: Take first dose on an empty stomach first thing in the morning, 45 minutes before a meal. On non-workout days, take second dose in same fashion. On workout days, take second dose 45 minutes before workout, on an empty stomach. Take third dose on an empty stomach 45 minutes before bed time for maximal effectiveness.

    Q: How long will it take me to notice the positive anabolic benefits from IGF-2?

    A: You will begin to feel the testosterone and growth hormone increases from IGF-2 about 7-10 days after beginning the product, at which point you will notice measurable increases in strength and size. By the end of the third week, you’ll be feeling the full effects of this amazing product with ever-increasing gains in strength, size and density.

    Q: What makes IGF-2 different from other anabolics on the market?

    A: Not to be cynical, but this one actually works. We are proud that this product delivers exactly what we claim it to. The specifically titrated ratios of the compounds in IGF-2 trigger enormous increases in growth hormone and testosterone production, while serving a critical anti-catabolic function as well. Users of IGF-2 generally report lean body mass gains of 5-7 lbs. over an 8 week cycle, with even greater gains being reported when stacked with NeoVar, our advanced creatine product.

    Q: How does IGF-2 boost testosterone levels, and how does testosterone grow more muscle?

    A: The safed musli componet of IGF-2 contains large amounts of spirosta-steroidal saponins (desoxydiosgenin, tigogenin and neotigogenin) which are intermediates to various hormonal pathways in the body. When ingested, desoxydiosgenin from the safed musli is enzymatically converted to 11-oxa-5 alpha-androstane-3,17-dione, a portion of which is converted to testosterone through the testes. The testosterone produced binds to the androgen receptor, which signals the muscles via mRNA to increase protein synthesis, increased nitrogen retention and muscle cell hypertrophy; leading to greater strength, mass, and recovery.

    Q: How does the L-Dopa in IGF-2 help with testosterone production and growth hormone secretion?

    A: The variety of mucuna pruriens used in IGF-2™ is standardized to 25% L-Dopa, delivering large amounts of this active ingredient per capsule. Two important mechanisms of action of L-Dopa is increased growth hormone (GH) release, and increased testosterone secretion through prolactin inhibition. Prolactin is a hormone that regulates testosterone production, and too much of it can hinder testosterone production. By inhibiting prolactin, IGF-2 increases endogenous testosterone levels dramatically. L-Dopa is a precursor to Dopamine, a potent GH and testosterone agonist, meaning that dopamine inhibits prolactin release and somatostatin secretion in the hypothalamus, which allows for a greater stimulatory effect of growth hormone-releasing hormone (GHRH) and secretion of testosterone by the testes. GHRH signals the pituitary to release GH, which is produced by the pituitary gland. GH is an important anabolic hormone that stimulates skeletal muscle cells to grow and, in some cases, divide. Acting directly, GH also mobilizes fats from fat depots and decreases the rate of glucose intake and metabolism.


    Q: What anabolic and energy-enhancing actions does rhodiola rosea have?

    A: Rhodiola rosea has been shown to increase ATP (Adenosine Triphosphate) production in the mitochondria of the cell. ATP is an energy molecule that allows for muscle contraction to occur. In a university study, mice were administered rhodiola and made to swim to exhaustion twice a day for six days. At the end of the testing period, muscle biopsies were performed, with the rhodiola-treated mice having 17% greater ATP levels, 45% greater creatine phosphate stores, and 53% greater muscle glycogen levels, along with lowered intramuscular concentrations of lactic acid and ammonia. What this means to you is stronger muscle contraction, allowing for improved energy and stamina.

    In human studies, the rosavin and salidroside found in rhodiola rosea have also been shown to have significant effects on stress reduction. This is accomplished by reducing cortisol release, while optimizing levels of key brain chemicals involved in mood, such as serotonin and dopamine, which function together to maintain a healthy response to stress. Blocking cortisol is important, as cortisol tends to break down muscle tissue, increase body fat stores, slows the metabolism and lowers immune function. Rhodiola has been shown to have adaptogenic qualities, meaning that it allows humans to work harder during stress, while at the same time maintaining higher energy reserves.

    Q: Should I cycle IGF-2?

    A: Yes- we recommend that IGF-2 be taken in 8-10 week cycles to maximize effectiveness. The user should allow thirty days to pass before commencing a new cycle. Many use a two months on, one-month off philosophy with outstanding results.

    Q: Who can benefit from IGF-2?

    A: Any serious athlete or bodybuilder looking to gain size and/or strength and speed recovery time. Endurance athletes can also benefit from IGF-2 as well; testing with IGF-2 was performed on Olympic-level track athletes who experienced measurable incremental improvements in speed plus reductions in muscle fatigue. Extensive testing has been also been conducted with nationally-ranked and IFBB pro bodybuilders and competitive power lifters, and the results in terms positive effects/benefits have been phenomenal. Additionally, all ingredients comply with IOC, NCAA, NFL, NBA, and MLB banned substances lists.
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    do i need to take a PCT after the cycle and if so what do you recommend. and thanks backer for writing these up
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    NO pct is not necessary if anything this can be used in conjunction with a proper pct cycle. orstand alone.

    all ingredients are natural
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    Wildor,

    No PCT is necessary whatsoever. Cycling it is recommended however, to ensure your body doesn't overly adapt.
    Applied Nutriceuticals Representative
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    If this was a gunfight, I'd be dead. lol
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    hahaha thanks guys
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    Would it be beneficial to take IGF-2 with an AI such as (Rebound Reloaded or Hyperdrol) or would this negate some of the positives seen with this product.
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    Quote Originally Posted by bludevil View Post
    Would it be beneficial to take IGF-2 with an AI such as (Rebound Reloaded or Hyperdrol) or would this negate some of the positives seen with this product.
    It would probably be ok, BUT AI's tend to have the habit of drying out the joints, and the inclusion of Rhodiola (which inhibits cortisol, which is needed to cushion the joints) could possibly dry them out even more.
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    just curious...at the top of the thread it says to take on an empty stomach 45 minutes before eating. At the bottom of the thread it says to take with food...which is it?
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    Deadlifter,

    Thank you for pointing that out!
    Originally when written up, the FAQ for IGF-2 stated to take the supplement with food. It was discovered through quite a bit of use and feedback that results were greatly increased when the product was taken on an empty stomach. The revised, current FAQ calls for an empty stomach for best results.
    Hope this helps, and thank you for bringing that to our attention.
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    lol, glad to help but....im not sure you actually answered the question! You said ...ORIGINALLY the FAQ said best taken on an empty stomach, then said it was discovered after alot of feedback that it was best taken on an empty stomach, and the revised FAQ says take an an empty stomach. LOL Im assuming you meant originally the FAQ said take with food, and then it was discovered that it was best to take on an empty stomach? I guess the bottom line though is...TAKE ON AN EMPTY STOMACH!
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    Quote Originally Posted by deadlifter25 View Post
    lol, glad to help but....im not sure you actually answered the question! You said ...ORIGINALLY the FAQ said best taken on an empty stomach, then said it was discovered after alot of feedback that it was best taken on an empty stomach, and the revised FAQ says take an an empty stomach. LOL Im assuming you meant originally the FAQ said take with food, and then it was discovered that it was best to take on an empty stomach? I guess the bottom line though is...TAKE ON AN EMPTY STOMACH!

    I think that's a good sign I need a nap. haha. Ok, now to do some revising.....
    Thanks man! Yes, Take on an empty stomach :-)
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    haha...its sunday, great day for a nap! So id gladly take a couple of free bottles for my trouble and do a log. lol, nah...but i might use this product in PCT for a cycle im lookin at putting together (or as a stand alone just incase your feelin extra sleepy and generous right now) lol
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    Let's see what we can work out for you Deadlifter.........
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    wow, you'd be the F'n man...!
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    Hit me up at Lanbane (at) aol (dot) com
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    ok, email sent
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    So i feel like im cluttering up this FAQ here, but i just wanted to thank Lanbane and say that i will be starting an IGF-2 and NeoVar log in the very near future. And i cant wait!
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    Quote Originally Posted by deadlifter25 View Post
    So i feel like im cluttering up this FAQ here, but i just wanted to thank Lanbane and say that i will be starting an IGF-2 and NeoVar log in the very near future. And i cant wait!
    We are looking forward to it as well!!
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    another question, would IGF-2 help with libido and wood?
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    Blu, Does a bear shi........... I mean.... ;-)

    Yes, yes it will help.
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    cool, looking forward to giving it a try.
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    Hey,

    I dont have time to wait forty five minutes to take Igf-2 on an empty stomach, plain and simple. Im simply busy . Can I take it after my meals and will it be effective?
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    Quote Originally Posted by smeton_yea View Post
    Hey,

    I dont have time to wait forty five minutes to take Igf-2 on an empty stomach, plain and simple. Im simply busy . Can I take it after my meals and will it be effective?

    Yes, it will still be extremely effective- the empty stomach recommendation is for maximum effectiveness.
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    here's a question i've yet to see asked, and i'm curious cuz i wanna try this:

    here' s my q....

    right now i'm in the middle of this cycle: (test cyp-600/week, eq-400/week, winny 60/day) and i just got off receptor grade igf-lr3 @ 50mcg/post workout on training days.....

    now, can i take this igf-2 stuff and make my cells swell up while i'm on this cycle and my new baby cells from the previous igf run are fresh? lemme know cuz if not i'll wait but i'm interested in this! thanks!
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    Quote Originally Posted by freakboy View Post
    here's a question i've yet to see asked, and i'm curious cuz i wanna try this:

    here' s my q....

    right now i'm in the middle of this cycle: (test cyp-600/week, eq-400/week, winny 60/day) and i just got off receptor grade igf-lr3 @ 50mcg/post workout on training days.....

    now, can i take this igf-2 stuff and make my cells swell up while i'm on this cycle and my new baby cells from the previous igf run are fresh? lemme know cuz if not i'll wait but i'm interested in this! thanks!
    IGF-2 would be good for post-cycle to preserve your gains- are you training for a bb.comp? Those doses are up there
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    Quote Originally Posted by rms80 View Post
    IGF-2 would be good for post-cycle to preserve your gains- are you training for a bb.comp? Those doses are up there
    well, the thing is, is i'll be taking more IGF-LR3 receptor grade @ 50mcg/post workout again during PCT. Can i take both kinds of igf and experience more benefit?

    yes, bodybuilding and powerlifting. I actually just won a comp this weekend. Took first weighing in at 198lb deadlifting 520lbs to win. IT was an easy win, i didn't even have to do my last lift haha
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    IGF-1 and the AN product "IGF-2" are not the same class...IGF-1 is a hormone, IGF-2 is a herbal supplement. No issues...
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    FREAKBOY!! pulling off a big powerlifting win at your first meet!!:dl:

    Ya freak adding IGF2 wont be a problem you will probably see different effects you wouldnt get from just the real IGF take them both and supply some feedback you punk haha!!
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    haha thanks man! ok i'll take em both in my pct along with neovar, and let ya's know what happens.
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    How's IGF-2 on a cut, you recommend?
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    Quote Originally Posted by bludevil View Post
    How's IGF-2 on a cut, you recommend?
    Oh yeah- stack it with RPM and you will be VERY happy with the results!!!
    Dirk Tanis, BA, MSci
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    how should it be dosed if you workout in the morning. i am assuming your first dose would be upon wakening, then should the second dose be followed post-workout or wait until before lunch time? i will also be taking neovar so dunno if it would be good to take both that and the igf2 post wo if i train in the morning.
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    Quote Originally Posted by vtstone View Post
    how should it be dosed if you workout in the morning. i am assuming your first dose would be upon wakening, then should the second dose be followed post-workout or wait until before lunch time? i will also be taking neovar so dunno if it would be good to take both that and the igf2 post wo if i train in the morning.
    Just wait until your post-workout meal to dose NeoVar if you work out in the morning-

    BUT- take the IGF-2 first thing when you get up, preferably with RPM
    Dirk Tanis, BA, MSci
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    Have a question. I'm dosing RPM and IGF-2 currently. I've been noticing my loads have been increasing. Is this due to IGF-2. My libido has not increased that much, but I have noticed a considerable increase in the money shot. My wife even commented on the amount she's having to wipe off. She stated last night "Why do you have this much coming out of you, it's not been that long since we've had sex"
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    Did you run RPM without IGF-2 previously with no increases?

    I can say that while on the same combo, I experienced the same.... with the added bonus of more force/distance. RPM alone does the same for me to a slightly lesser degree.
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    Quote Originally Posted by Lanbane View Post
    Did you run RPM without IGF-2 previously with no increases?

    I can say that while on the same combo, I experienced the same.... with the added bonus of more force/distance. RPM alone does the same for me to a slightly lesser degree.

    Yeah I think your right. It must be the combo that has the effect. I've ran IGF-2 before but not at the amount I'm doing now. Currently I'm dosing 1.5 times the amount on the dosage chart. I thought maybe the increase in pills was causing the effect but I guess the Icarrin in RPM could be doing it as well.
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    Quote Originally Posted by Ziricote View Post
    IGF-1 and the AN product "IGF-2" are not the same class...IGF-1 is a hormone, IGF-2 is a herbal supplement. No issues...
    i don't doubt that IGF-2 is a great product as AN is a great company.
    but i have to be honest - i can't stand the name IGF-2.
    it puts your product name on the same level as those stupid products that try and copy names of real AAS.
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    These Sides from L-Dopa have me a little worried are the mentioned inhibitors in this product? This is from Wikipedia.


    Levodopa(L-Dopa) is used as a prodrug to increase dopamine levels for the treatment of Parkinson's disease, since it is able to cross the blood-brain barrier whereas dopamine itself cannot. Once levodopa has entered the central nervous system (CNS), it is metabolized to dopamine by aromatic L-amino acid decarboxylase. However, conversion to dopamine also occurs in the peripheral tissues, causing adverse effects and decreasing the available dopamine to the CNS, so it is standard practice to co-administer a peripheral DOPA decarboxylase inhibitor – carbidopa or benserazide – and often a catechol-O-methyl transferase (COMT) inhibitor.

    Adverse effects

    Possible adverse drug reactions include:

    * Hypotension, especially if the dosage is too high.
    * Arrhythmias, although these are uncommon.
    * Nausea, which is often helped by taking the drug with food, although protein interferes with drug absorption.
    * Gastrointestinal bleeding.
    * Disturbed respiration. This is not always harmful, and can actually benefit patients with upper airway obstruction.
    * Hair loss.
    * Confusion.
    * Extreme emotional states, particularly anxiety, but also excessive libido.
    * Vivid dreams and/or fragmented sleep.
    * Visual and possibly auditory hallucinations.
    * Effects on learning. There is some evidence that it improves working memory, while impairing other complex functions.
    * Sleepiness and sleep attacks.
    * a condition similar to amphetamine psychosis.

    Although there are a number of adverse effects associated with levodopa, particularly psychiatric ones, it has fewer than other anti-Parkinson's drugs, including anticholinergics, amantadine, and dopamine agonists.

    More serious are the effects of chronic levodopa administration, which include:

    * End-of-dose deterioration of function.
    * On/off oscillations.
    * Freezing during movement.
    * Dose failure (drug resistance).
    * Dyskinesia at peak dose.

    Clinicians will try to avoid these by limiting levodopa dosages as far as possible until absolutely necessary.
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