We all know what DAA is, but for the new guys:
D-Aspartic Acid is a naturally occuring form of an amino acid. It is created when the enzyme aspartate racemase converts L-aspartic acid into D-aspartic acid. D-aspartic acid is primarily located in neuroendocrine tissues such as the hypothalamus and pituitary gland.
When ingesting d-aspartic acid, it is primarily absorbed by these very tissues, where it then binds to the n-methyl-d-asparate (NMDA) receptor. Research shows that activation of these receptors is crucial to testosterone release, and some data even shows that if its blocked it can even REDUCE testosterone. (1)Once this binding has taken place, concentrations of gonadotropin-releasing hormone (GnRH) increase. The increase in GnRH signals the pituitary to release the signalling messengers leutinizing hormone (LH) and follicle-stimulating hormone (FSH). LH and FSH then signal the testes to initiate a sequence called "steroidogenisis", or testosterone creation.
A study conducted in Italy on healthy young men used 3.12g of sodium d-aspartic acid daily and monitored hormone concentrations. By twelve days, testosterone had increased by an average of 40%.(2)
1.Blockage of N-methyl-D-aspartate receptor... [Neuroendocrinology. 2000] - PubMed - NCBI
2.The role and molecular mechanism of D... [Reprod Biol Endocrinol. 2009] - PubMed - NCBI
