Synthetic Supplements - Methyl-Synephrine Tabs

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    Synthetic Supplements - Methyl-Synephrine Tabs


    This is a one time run of Methyl-Synephrine Tablets. Great Price. Great Quality.

    If you ever may want MS Tabs I suggest you pick some up...once they are gone they are gone.

    60 x 60mg tablets.

    Max dosing is 60mg 2x per day. Start off with 1/2 tablet to assess tolerance.

    Combine with caffeine for the same MoA as EC Stack.

    Methyl-Synephrine

    They will also be at the Planet today
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    Synephrine is an adrenergic agonist that has gained popularity as being an alternative to ephedrine. It is found in many species of plants, however the main source today for synephrine is citrus aurantium, also known as “bitter orange”. Once the ephedra ban took place, many supplement retailers switched ingredients to synephrine or methyl-synephrine for their fat loss products.

    Methyl-synephrine differs from standard synephrine in that it contains a superior chemical structure. Data suggests that this not only inhibits MAO activity, but also increases the compounds affinity for the beta-adrenergic receptors. It is often compared to octopamine and suggested to primarily activate beta-3 receptors.
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    Looks good, but I would have to say that is a company name BEGGING for scrutiny.
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    Would this work well with Alpha T-2? Or save it for later?
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    Quote Originally Posted by Geoforce View Post
    Would this work well with Alpha T-2? Or save it for later?
    Actually Methyl-Syn was int he OG aT2 and I see many are now building their OG aT2 from the ingredients we offer.
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    Quote Originally Posted by nattydisaster View Post


    Synephrine is an adrenergic agonist that has gained popularity as being an alternative to ephedrine. It is found in many species of plants, however the main source today for synephrine is citrus aurantium, also known as “bitter orange”. Once the ephedra ban took place, many supplement retailers switched ingredients to synephrine or methyl-synephrine for their fat loss products.

    Methyl-synephrine differs from standard synephrine in that it contains a superior chemical structure. Data suggests that this not only inhibits MAO activity, but also increases the compounds affinity for the beta-adrenergic receptors. It is often compared to octopamine and suggested to primarily activate beta-3 receptors.

    mmm, methyl synephrine!
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    Quote Originally Posted by DAdams91982 View Post
    Actually Methyl-Syn was int he OG aT2 and I see many are now building their OG aT2 from the ingredients we offer.
    How much MS would you recommend?
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    Quote Originally Posted by Geoforce View Post
    How much MS would you recommend?
    When stacking it with AT2?
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    Sounds like nice product. I take it this would be good to stack with something like Alphaburn or sns yohimbe hcl for fat loss?
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    Quote Originally Posted by kevinhy View Post
    When stacking it with AT2?
    Yeah. Currently running an Alpha t2 log for you guys. Probably wont stack my log bottle with ms, but for future knowledge
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    Interesting.
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    Quote Originally Posted by Thepaul7 View Post
    Sounds like nice product. I take it this would be good to stack with something like Alphaburn or sns yohimbe hcl for fat loss?
    Yup!

    Quote Originally Posted by Geoforce View Post
    Yeah. Currently running an Alpha t2 log for you guys. Probably wont stack my log bottle with ms, but for future knowledge
    I would probably only had 1/2 tab each dose of Alpha-T2, for a total of 60mg methyl syn per day.
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    Just in time to cut some additional BF as the weather warms up!
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    Very nice
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    I'm in love <3 this makes for a kick ass stack with caffeine and AT2 , throw in EP for lean dryness!!! PES always comes up with the supplements I need to keep it natty and never have to consider PHs <3!!!
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    Quote Originally Posted by Geoforce View Post
    Yeah. Currently running an Alpha t2 log for you guys. Probably wont stack my log bottle with ms, but for future knowledge
    Full-dosed MS with caffeine will actually be much more effective than Alpha-T2. I will be picking up a few bottles as this is pretty much the best supplemental fat-burning ingredient we have at our disposal currently (not counting ephedrine).
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    AT2 doesnt have methyl synephrine in it? Just goes to show Im understocked on it.

    I like MS. Its good stuff. That brand name will certainly have some heads turning.
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    Dooooo waannnntt, but not at the planet, Natty, damn iittttttt.
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    Nevermind, found it.
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    Sorry. Posted this in wrong thread initially.

    Want to create a stack once I get off AI. Been on it for 8 weeks. Following are already in plan.

    Alpha T2
    Oxyelite Pro
    Compound 20

    Can I add Methyl Synephrine to this ?

    If not, what should it replace ? I am assuming OEP.

    If you think it should replace OEP, why ? If not why ?

    FYI- I am very tolerant to stims. I can take OEP 30 minutes prior to sleep and have no issues.

    Thank you in advance.
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    I would choose either AT2 or OEP + MS, but not all three
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    Quote Originally Posted by fumoney View Post
    Sorry. Posted this in wrong thread initially.

    Want to create a stack once I get off AI. Been on it for 8 weeks. Following are already in plan.

    Alpha T2
    Oxyelite Pro
    Compound 20

    Can I add Methyl Synephrine to this ?

    If not, what should it replace ? I am assuming OEP.

    If you think it should replace OEP, why ? If not why ?

    FYI- I am very tolerant to stims. I can take OEP 30 minutes prior to sleep and have no issues.

    Thank you in advance.
    I would pick either AT2 or OEP to stack with Methyl synephrine. I feel all three together would just be too much.
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    We are OOS on Synthetic website...last remaining bottles were sent to retailers today. Small run, for the hardcore AM guys!
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    Is this alpha-methyl-synephrine or Beta-O-Methyl-Synephrine?
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    Quote Originally Posted by tobicles View Post
    Is this alpha-methyl-synephrine or Beta-O-Methyl-Synephrine?
    Alpha!
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    Anyone provide any feedback on MS?
    I know Natty send out some bottles a while back and I was curious to experiences.
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    Quote Originally Posted by AaronJP1 View Post
    Anyone provide any feedback on MS?
    I know Natty send out some bottles a while back and I was curious to experiences.
    Ran a bottle and the stimulant effect was small to nill for me. As for the fat burning not really sure. Didn't notice anything out of the ordinary.
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    Quote Originally Posted by Geoforce View Post
    Ran a bottle and the stimulant effect was small to nill for me. As for the fat burning not really sure. Didn't notice anything out of the ordinary.
    What was your dosing?
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    Quote Originally Posted by ax1 View Post
    What was your dosing?
    2 tabs a day. It was added to Alpha T-2. Thought I noticed a slight difference early on, but it dissipated. Still have a bottle left might run it with caffeine tabs at 1.5 a dose.
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    Quote Originally Posted by Geoforce View Post
    2 tabs a day. It was added to Alpha T-2. Thought I noticed a slight difference early on, but it dissipated. Still have a bottle left might run it with caffeine tabs at 1.5 a dose.
    Your not using caffeine with each dose?
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    Quote Originally Posted by ax1 View Post
    Your not using caffeine with each dose?
    I did for about the last half of the bottle as I was logging AT-2. Take it that might have been a mistake from your tone

    FWIW I may have needed a big stim break when I took it.

    Your results/experiences with MS?
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    Quote Originally Posted by ax1

    Your not using caffeine with each dose?
    I just got a bottle...is this supposed to be dosed with caffeine for maximum effectiveness?
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    Quote Originally Posted by Geoforce View Post
    I did for about the last half of the bottle as I was logging AT-2. Take it that might have been a mistake from your tone

    FWIW I may have needed a big stim break when I took it.

    Your results/experiences with MS?
    I havent taken it standalone as its easy for me to use ec, but Im open for trying it out in the future. I should get a couple of bottles before (in case) they are gone.

    I did have good experience with the very original Alpha T-2 but that has other things in it as well and the MS. I dont recall how much MS was in Alpha T-2, but I think it had 30mg and with added caffeine should be a decent enough dose to have effect, although 60mg should be much better I heard.

    Quote Originally Posted by uvawahoowa View Post
    I just got a bottle...is this supposed to be dosed with caffeine for maximum effectiveness?
    I think 60mg with 200mg caffeine is an effective dose. There isnt research with stacking MS with caffeine the same way there is with EC, but 60MS/200C should be something I personally would do.

    Quote Originally Posted by neuron
    Caffeine is definitely a must with methylsynephrine. Even ephedrine itself has demonstrated weak lipolytic inducing potential in the absence of caffeine. This makes sense as caffeine potentiates the transduction (Gs) mechanism involved in fat loss (inc. cAMP).
    Quote Originally Posted by neuron
    One of the things which I wanted to elaborate upon was the transduction mechanisms inherent to different adrenergic receptors.

    For example, alpha1-receptors activate the IP3-DAG transduction cascade which ultimately results in calcium release and contraction/vasoconstriction (in smooth muscle). This mechanism is potentiated by caffeine co-consumption since caffeine enhances calcium release. Conversely, beta-receptors (all three of them) work through elevation of intracellular cAMP. Since caffeine also functions as a PDEi, cAMP levels will be prolonged. This explains why ephedrine alone (a beta-3 agonist) is only a weak lipolytic-inducing agent, but extremely potent in concert with caffeine.

    Here's a good reveiw: http://www.sciencedirect.com/science...ca039e1e6c4368

    Quote Originally Posted by neuron
    Synephrines downsides
    Increasing peripheral vascular resistance is a negative characteristic of a lot of stimulants and is especially exacerbated in compounds which primarily activate alpha-receptors like synephrine. Not only is the incidence of stroke and hemorrhage higher with these agents, but the work-load put on the heart can trigger ventricular fibrillations or other arrhythmias [6, 7, 8]. Using caffeine in conjunction with synephrine will potentiate the peripheral vasoconstriction by synergizing with the transduction mechanism induced by alpha-adrenergic agonism [9, 10]. Adrenergic agonists with high affinity to alpha-receptors also have the unfortunate capacity to induce platelet aggregation by agonizing alpha-2 receptors on platelets which can lead to intravascular clotting [11, 12].
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    Quote Originally Posted by ax1

    I havent taken it standalone as its easy for me to use ec, but Im open for trying it out in the future. I should get a couple of bottles before (in case) they are gone.

    I did have good experience with the very original Alpha T-2 but that has other things in it as well and the MS. I dont recall how much MS was in Alpha T-2, but I think it had 30mg and with added caffeine should be a decent enough dose to have effect, although 60mg should be much better I heard.

    I think 60mg with 200mg caffeine is an effective dose. There isnt research with stacking MS with caffeine the same way there is with EC, but 60MS/200C should be something I personally would do.
    Very interesting... good thing I saw this thread. For recomp or cutting, is this better pre meal or pre cardio?
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    Quote Originally Posted by uvawahoowa View Post
    Very interesting... good thing I saw this thread. For recomp or cutting, is this better pre meal or pre cardio?
    I dont think either necessarily matters, but taking it with caffeine is crucial. Think about how many people take ephedrine without caffeine. None.
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    Quote Originally Posted by uvawahoowa View Post
    Very interesting... good thing I saw this thread. For recomp or cutting, is this better pre meal or pre cardio?

    Id dose 3 times a day. You can take it pre-workout which makes sense since if you like taking stims pre-workout it just makes for good timing (and eliminate the 4th dose in that day of taking a stim). You want to make sure your in a good state of health and dont run into blood pressure issues when taking pre-training.

    If you want the best effect I would take it fasted on an empty stomach. Some people such as myself cant take caffeine in such a way due to a nauseating effect from the caffeine so I take my ephedrine with coffee for example, the half and half makes a dramatic difference for me.
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    Quote Originally Posted by Geoforce View Post
    Ran a bottle and the stimulant effect was small to nill for me. As for the fat burning not really sure. Didn't notice anything out of the ordinary.
    MS doesn't penetrate the BBB so this isn't surprising. It should, however, promote lipolysis.
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    Quote Originally Posted by ax1

    Id dose 3 times a day. You can take it pre-workout which makes sense since if you like taking stims pre-workout it just makes for good timing (and eliminate the 4th dose in that day of taking a stim). You want to make sure your in a good state of health and dont run into blood pressure issues when taking pre-training.

    If you want the best effect I would take it fasted on an empty stomach. Some people such as myself cant take caffeine in such a way due to a nauseating effect from the caffeine so I take my ephedrine with coffee for example, the half and half makes a dramatic difference for me.
    So would it be 20mg ms plus 100mg caffeine each dose?
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    Quote Originally Posted by uvawahoowa View Post
    So would it be 20mg ms plus 100mg caffeine each dose?
    IMO I would do 60/200 two to three times a day. 20mg is a bit weak.

    I think those caps that are available are 60 mg each so thats perfect.
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