There are various observations which, taken as a whole, suggest (to me at least) that a steady state of elevated tonus is very hypertrophy inducing in muscles. In other words, a constantly elevated muscle tension results in growth. The strongest scientific support for this comes from the famous bird study, where a constant stretch of their chest muscles resulted in -as far as I know- pretty much the fastest muscular hypertrophy ever on record. (this is a neat link with several relevant studies: Precision Nutrition Coaching | Forums | Loaded stretching = hypertrophy and hyperplasia I did not want clutter this thread by posting them all here).
It is also interesting to note that people tend to report constant tension (a constant pumped feeling) from many potent AAS, and -among others of course- this may be one of the MOAs that steroids are causing muscle growth. We also know how fat guys can develop amazing calves without ever doing a set of calf work in the gym.
My question is: Can you think of a (relatively) safe biochemical method of inducing an elevated tension in the muscles at rest, without going through the AR? Do you consider such a route feasible and/or worthy of study?
Thank you very much for your time and attention