NMT Headaches... Anyone else?

  1. Registered User
    Ceredumbellum's Avatar
    Stats
    5'10"  200 lbs.
    Join Date
    Aug 2012
    Location
    Kansas City
    Age
    34
    Posts
    183
    Rep Power
    31755

    NMT Headaches... Anyone else?


    Just curious if anybody else has gotten wicked headaches when taking N-Methyltyramine (NMT). I've tried it as a stand alone as well as in proprietary blends and everytime, without exception, I get a nasty headache. I've read about its' supposed benefits as a dietary supplement but, for me anyway, the side effects outweight any benefit. Curious if anybody knows why it causes these headaches (I have yet to find any solid data regarding this).

  2. Featured Author
    Patrick Arnold's Avatar
    Join Date
    Apr 2007
    Posts
    4,119
    Rep Power
    554323

    Quote Originally Posted by Ceredumbellum View Post
    Just curious if anybody else has gotten wicked headaches when taking N-Methyltyramine (NMT). I've tried it as a stand alone as well as in proprietary blends and everytime, without exception, I get a nasty headache. I've read about its' supposed benefits as a dietary supplement but, for me anyway, the side effects outweight any benefit. Curious if anybody knows why it causes these headaches (I have yet to find any solid data regarding this).

    tyramine is well known for the "cheese effect" which usually comes on with people that are on MAO inhibitors. tyramine can be a potent vasoconstrictor if MAO does not act on it.

    I dunno if this has anything to do with NMT but its likely that it too has the potential to do the same. NMT is just a nasty ingredient. There is little positive in the way of pharmacological properties and much negative
    Anabolicminds.com Featured Author
  3. Registered User
    Ceredumbellum's Avatar
    Stats
    5'10"  200 lbs.
    Join Date
    Aug 2012
    Location
    Kansas City
    Age
    34
    Posts
    183
    Rep Power
    31755

    Thanks for the info. PA.
    I remember how, right after the Ephedra ban, it seemed like almost every supplement company felt compelled to dump a bunch of Yohimbe into their proprietary blends. It ruined so many thermogenics that would have otherwise been decent without a bunch of Yohimbe. It seems like the same approach is being taken with NMT in regard to DMAA possibly being banned.
    •   
       

  4. Featured Author
    Patrick Arnold's Avatar
    Join Date
    Apr 2007
    Posts
    4,119
    Rep Power
    554323

    Quote Originally Posted by Ceredumbellum View Post
    Thanks for the info. PA.
    I remember how, right after the Ephedra ban, it seemed like almost every supplement company felt compelled to dump a bunch of Yohimbe into their proprietary blends. It ruined so many thermogenics that would have otherwise been decent without a bunch of Yohimbe. It seems like the same approach is being taken with NMT in regard to DMAA possibly being banned.
    yes lipo 6, redline, etc. all were full of yohimbine. i stayed away from yohimbine and always have. The stuff personally makes me feel ill. Some dont mind it but many get sick from it. why they go after DMAA and not that poison i dunno

    NMT is not as dangerous as yohimbine, but its still a dirty stim
    Anabolicminds.com Featured Author
  5. Registered User
    Ceredumbellum's Avatar
    Stats
    5'10"  200 lbs.
    Join Date
    Aug 2012
    Location
    Kansas City
    Age
    34
    Posts
    183
    Rep Power
    31755

    Quote Originally Posted by Patrick Arnold View Post
    yes lipo 6, redline, etc. all were full of yohimbine. i stayed away from yohimbine and always have. The stuff personally makes me feel ill. Some dont mind it but many get sick from it. why they go after DMAA and not that poison i dunno

    NMT is not as dangerous as yohimbine, but its still a dirty stim
    My thoughts exactly. Every time I've ever taken Yohimbe I've always gotten very naseous and "shaky"- I'd be burning up and sweating my ass off but my teeth would be chattering like I was freezing. The only thing it really did any good for was as a sexual aid but, again, I'd be so sick I couldn't put it to good use! Lol...
    But back to NMT... I'll never take a supplement that contains that crap again. Too many negatives(including the worst headaches I've ever experienced) and no positives; at least not for me. Thanks for the info. PA.
  6. Featured Author
    Patrick Arnold's Avatar
    Join Date
    Apr 2007
    Posts
    4,119
    Rep Power
    554323

    Quote Originally Posted by Ceredumbellum View Post
    My thoughts exactly. Every time I've ever taken Yohimbe I've always gotten very naseous and "shaky"- I'd be burning up and sweating my ass off but my teeth would be chattering like I was freezing. The only thing it really did any good for was as a sexual aid but, again, I'd be so sick I couldn't put it to good use! Lol... .
    lol my exact experience when i took my first sample of redline. i had to leave the gym and go to bed and shiver and sweat. with an erection. wonderful
    Anabolicminds.com Featured Author
  7. Registered User
    Kelt's Avatar
    Stats
    6'0"  227 lbs.
    Join Date
    Feb 2008
    Location
    Sweden
    Age
    36
    Posts
    36
    Rep Power
    97

    Quote Originally Posted by Patrick Arnold View Post
    lol my exact experience when i took my first sample of redline. i had to leave the gym and go to bed and shiver and sweat. with an erection. wonderful
    Could these adverse effects perhaps be because Yohimbine is a tryptamine related compound that fiddles with way too many types of 5-HT serotonergic receptors?
  8. Registered User
    Kelt's Avatar
    Stats
    6'0"  227 lbs.
    Join Date
    Feb 2008
    Location
    Sweden
    Age
    36
    Posts
    36
    Rep Power
    97

    Quote Originally Posted by Ceredumbellum View Post
    My thoughts exactly. Every time I've ever taken Yohimbe I've always gotten very naseous and "shaky"- I'd be burning up and sweating my ass off but my teeth would be chattering like I was freezing. The only thing it really did any good for was as a sexual aid but, again, I'd be so sick I couldn't put it to good use! Lol...
    But back to NMT... I'll never take a supplement that contains that crap again. Too many negatives(including the worst headaches I've ever experienced) and no positives; at least not for me. Thanks for the info. PA.
    What you are describing here does fit the descriptions for symptoms of serotonin syndrome. At least for the autonomic effect part.
  9. Registered User
    tigerbunny's Avatar
    Join Date
    Jan 2008
    Posts
    115
    Rep Power
    6694

    I think most people overdose yohimbine. 2.5-5 mg is all thats needed but alot of companies seem to put a lot more than that. I find the best application to be with EC, IE 25mg E/200mg C/ 2.5 mg Y, at that dose it has a nice synergy with EC and dosn't cause all the bad sides.
  10. Registered User
    Ceredumbellum's Avatar
    Stats
    5'10"  200 lbs.
    Join Date
    Aug 2012
    Location
    Kansas City
    Age
    34
    Posts
    183
    Rep Power
    31755

    Quote Originally Posted by tigerbunny View Post
    I think most people overdose yohimbine. 2.5-5 mg is all thats needed but alot of companies seem to put a lot more than that. I find the best application to be with EC, IE 25mg E/200mg C/ 2.5 mg Y, at that dose it has a nice synergy with EC and dosn't cause all the bad sides.
    I've always used as small a dose of Yohimbe as possible when I have used it. I think Yohimbe is unique in the sense that I've know people who it doesn't affect at all and then I've known guys that get side effects like I do and even worse in some cases. I am curious though.... You said when combinded with EC you love the synergysm and don't experience the nasty sides. Have you ever experience bad side effects from Yohimbe and, if so, how would combining it with EC reduce or eliminate those sides?
  11. Featured Author
    Patrick Arnold's Avatar
    Join Date
    Apr 2007
    Posts
    4,119
    Rep Power
    554323

    Quote Originally Posted by Ceredumbellum View Post
    I've always used as small a dose of Yohimbe as possible when I have used it. I think Yohimbe is unique in the sense that I've know people who it doesn't affect at all and then I've known guys that get side effects like I do and even worse in some cases. I am curious though.... You said when combinded with EC you love the synergysm and don't experience the nasty sides. Have you ever experience bad side effects from Yohimbe and, if so, how would combining it with EC reduce or eliminate those sides?

    thats interesting if its true
    Anabolicminds.com Featured Author
  12. Registered User
    Ceredumbellum's Avatar
    Stats
    5'10"  200 lbs.
    Join Date
    Aug 2012
    Location
    Kansas City
    Age
    34
    Posts
    183
    Rep Power
    31755

    Quote Originally Posted by Kelt View Post
    What you are describing here does fit the descriptions for symptoms of serotonin syndrome. At least for the autonomic effect part.
    I always understood Yohimbe to work primarily on Norepinephrine and not directly on Serotonin. Maybe I'm just flat wrong here or I'm simplifying this too much, but if I'm correct how could that cause Serotonin Syndrome? If it doesn't act directly on Serotonin how could it be Serotonin Syndrome since Serotonin is downstream from Dopamine and Norepinephrine (DA-> NE -> 5-HT)? If I'm way off on this feel free to educate me. My education is in Engineering, not Chemistry or Biology, but I'm always eager to learn.
  13. Registered User
    southpaw23's Avatar
    Stats
    5'11"  165 lbs.
    Join Date
    Jun 2010
    Posts
    3,376
    Rep Power
    1387262

    Quote Originally Posted by Patrick Arnold View Post
    lol my exact experience when i took my first sample of redline. i had to leave the gym and go to bed and shiver and sweat. with an erection. wonderful
    Story of my life.
  14. Registered User
    Ceredumbellum's Avatar
    Stats
    5'10"  200 lbs.
    Join Date
    Aug 2012
    Location
    Kansas City
    Age
    34
    Posts
    183
    Rep Power
    31755

    Quote Originally Posted by Patrick Arnold View Post
    lol my exact experience when i took my first sample of redline. i had to leave the gym and go to bed and shiver and sweat. with an erection. wonderful
    That's funny because I have a similar story you'd probably get a kick out of.... The last time that I took Yohimbe was a little over a year ago in some Stamina - RX (which was actually a really good product back around '02-'04 but is like injesting poison now). The story goes that I brought a chick back to my place after taking the Stamina - RX tablets and within 20 minutes of getting home I was so sick I couldn't do a damned thing with her! I'm laying there on my bed, curled up in the fetal posistion trying not to puke, all the while sporting a raging hard - on. She's stroking my head (the one up top) and asking me if I'm going to be ok and if there's anything she could do. Hahaha... What an f'ed up experience that was... Needless to say nothing very fun went down that night! After that experience I swore Yohimbe off forever. Now when I feel I need a bit of a sexual pick me up I just buy a decent herbal blend (obviously without Yohimbine) and stack it with 30mg of good ol' Cialis!
  15. Registered User
    Ceredumbellum's Avatar
    Stats
    5'10"  200 lbs.
    Join Date
    Aug 2012
    Location
    Kansas City
    Age
    34
    Posts
    183
    Rep Power
    31755

    Quote Originally Posted by Ceredumbellum View Post
    I've always used as small a dose of Yohimbe as possible when I have used it. I think Yohimbe is unique in the sense that I've know people who it doesn't affect at all and then I've known guys that get side effects like I do and even worse in some cases. I am curious though.... You said when combinded with EC you love the synergysm and don't experience the nasty sides. Have you ever experience bad side effects from Yohimbe and, if so, how would combining it with EC reduce or eliminate those sides?
    This just triggered a quasi "Ah-Ha!" moment for me... I mentioned above that I used to take Stamina RX back in the early 2000's and thought it was a great product. Now I know they have always (allegedly) spiked this product with prescription ED drugs (the early version of the product was allegedly spiked with Cialis). I thought Stamina RX was a blessing from the heaven's back then because it worked so well and I didn't get any of the nasty Yohimbe sides when I took it. During this time period I was also taking some kind of ECA stack every day. I was juiced to the gills at the time and stimmed out on Ephedrine seven days a week. I don't remember EVER having the afformentioned Yohimbe side effects from the Stamina RX and I was taking that stuff every weekend and usually once during the week. But I also had Ephedrine in my system during these times. Very interesting indeed... Granted, that's just two of us who have experienced decreased sides when combined with Ephedrine, but to have NO sides back then (other than a little flushing of the face) and have such nasty reactions to it now (I don't take Ephedrine anymore and haven't for a long time) makes me think there is indeed something to it. It'd be interesting to find out what exactly that something is.
  16. Registered User
    Kelt's Avatar
    Stats
    6'0"  227 lbs.
    Join Date
    Feb 2008
    Location
    Sweden
    Age
    36
    Posts
    36
    Rep Power
    97

    Quote Originally Posted by Ceredumbellum View Post
    I always understood Yohimbe to work primarily on Norepinephrine and not directly on Serotonin. Maybe I'm just flat wrong here or I'm simplifying this too much, but if I'm correct how could that cause Serotonin Syndrome? If it doesn't act directly on Serotonin how could it be Serotonin Syndrome since Serotonin is downstream from Dopamine and Norepinephrine (DA-> NE -> 5-HT)? If I'm way off on this feel free to educate me. My education is in Engineering, not Chemistry or Biology, but I'm always eager to learn.
    I do not dare to educate anyone within chemistry. I myself am educated within electrical engineering, currently trying to finish my Ph.D. studies within applied signal processing. However I do not mind to debate matters which I am interested in since also I am eager to learn. And what better way of learning then describing own understanding of the specific subject to others, to be either agreed on or corrected. Hopefully in the end we all learn something new. I do apology if my previous statements here and in the DMAA thread seemed as a pure fact, which I clearly do not claim.

    I know Wikipedia is not the best source of the information, but it can point one in the right direction. If you read the pharmacology part under yohimbine it does state which serotonin 5-HT receptor it affects. If compared with the info in article on 5-HT receptors, the yohimbine is mentioned either as agonist or antagonist under many of the specific types of 5-HT receptors. Then if you read the symptoms of Serotonin syndrome you will find many of the side effects you and many others experience mentioned. I am not saying this may be 100% correct, rather that it could be a possible explanation. It is 1am in Sweden, but I can try to provide specific articles about this matter within near future.

    On a side note, I do not think it matters if the serotonin receptors are directly or indirectly affected to cause the serotonin syndrome. From what I can read, the serotonin syndrome can equally be caused by amphetamine or methylphenidate which only affects dopamine and norepinephrine receptors. So the serotonin receptors are probably affected though the chain of events you are describing. But in the end, the serotonin receptors are affected, which gives the possibility to cause serotonin syndrome.

    Regarding the varying reactions to yohimbine, I suppose, some people are more sensitive than others. I tried yohimbine two years back in the ALRIs Poison. The first three days it gave me loose or liquid bowel movements, after that no negatives. I got slightly stimulated in contrast to the global version of the Poison that had the yohimbine removed.
  17. Registered User
    Ceredumbellum's Avatar
    Stats
    5'10"  200 lbs.
    Join Date
    Aug 2012
    Location
    Kansas City
    Age
    34
    Posts
    183
    Rep Power
    31755

    Quote Originally Posted by Patrick Arnold View Post
    thats interesting if its true
    If you read my last post I can also attest to this being true. With Ephedrine = Little to no sides. Without Ephedrine = Feeling like death. It just took me a bit to remember because it had been so long since I combined Yohimbine and Ephedrine. Any ideas on why this would happen, PA?
  18. Featured Author
    Patrick Arnold's Avatar
    Join Date
    Apr 2007
    Posts
    4,119
    Rep Power
    554323

    Quote Originally Posted by Ceredumbellum View Post
    If you read my last post I can also attest to this being true. With Ephedrine = Little to no sides. Without Ephedrine = Feeling like death. It just took me a bit to remember because it had been so long since I combined Yohimbine and Ephedrine. Any ideas on why this would happen, PA?

    try it again to confirm. i certainly aint gonna take the chance

    why it would work i dunno. we need someone like neuron to answer that
    Anabolicminds.com Featured Author
  19. Registered User
    Ceredumbellum's Avatar
    Stats
    5'10"  200 lbs.
    Join Date
    Aug 2012
    Location
    Kansas City
    Age
    34
    Posts
    183
    Rep Power
    31755

    Quote Originally Posted by Patrick Arnold View Post
    try it again to confirm. i certainly aint gonna take the chance

    why it would work i dunno. we need someone like neuron to answer that
    Hahaha.... No fuc#*ing way! I don't want to take the chance that it was something else that was negating the sides and be curled up in bed wishing I was dead... No more Yohimbine for this fella. But after that post from tigerbunny about Ephedrine offsetting the sides it took me back about 8-9 years and I remember experiencing the same thing. In fact those were the ONLY times I didn't experience horrific side effects from Yohimbine. I should also add that I was usually drinking or drunk (though not always) with Ephedrine in my system when I would take it. Plus I was doing different cycles off and on throughout a five year period there, though I don't see how one's androgen levels would make a difference.
  20. Registered User
    Ceredumbellum's Avatar
    Stats
    5'10"  200 lbs.
    Join Date
    Aug 2012
    Location
    Kansas City
    Age
    34
    Posts
    183
    Rep Power
    31755

    Quote Originally Posted by Patrick Arnold View Post
    try it again to confirm. i certainly aint gonna take the chance

    why it would work i dunno. we need someone like neuron to answer that
    Ok PA, I went ahead and bit the bullet... I took 25mg of Ephedrine and some caffeine before me and the Mrs. went out last weekend. Halfway through our date I took a Cialis tablet and an herbal sex blend with Yohimbine in it.
    The results: No nasuea, no shiverring, no wishing I was dead because I felt so awful. On the contrary, I felt great with the exception of a horribly flushed face. The Mrs. was pretty satisfied at the end of the night, too.
    I would really be intersted in finding out what causes this phenomenon. I'd love to hear PA or Neuron's take on it.
  •   

      
     

Similar Forum Threads

  1. Tren E give anyone else massive headache?
    By depfreeman450 in forum Anabolics
    Replies: 6
    Last Post: 05-31-2010, 07:38 AM
  2. Anyone else here use 28 x 1/2" on your triceps
    By drveejay11 in forum Anabolics
    Replies: 7
    Last Post: 02-11-2003, 08:00 AM
  3. Anyone else used Fina W/ 1-T and 4AD trans?
    By macattack in forum Anabolics
    Replies: 23
    Last Post: 02-03-2003, 03:01 PM
  4. Anyone else getting viruses from here?
    By 1Fast400 in forum General Chat
    Replies: 12
    Last Post: 01-04-2003, 11:37 PM
  5. Anyone Else?
    By YellowJacket in forum General Chat
    Replies: 15
    Last Post: 12-19-2002, 06:25 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  

Log in

Log in