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DAA and Free T?

  1.  06-14-2012  08:22 AM
    Registered User coolbreeze's Avatar
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    DAA and Free T?


    Pat-

    Just wondering if DAA would give better results if I combined it with something to lower SHBG/ increase Free T? I'm assuming there are agents out there, like Nettle Root, that can do that?

    Thanks



  2.  06-14-2012  12:32 PM
    Registered User broons's Avatar
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    I'm not Pat, but my guess would be yes. That is, if you can find a high quality Nettle extract that actually has an efficacious amount of Divanil in it.

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  3.  06-15-2012  07:41 AM
    Featured Author Patrick Arnold's Avatar
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    Originally Posted by coolbreeze View Post
    Pat-

    Just wondering if DAA would give better results if I combined it with something to lower SHBG/ increase Free T? I'm assuming there are agents out there, like Nettle Root, that can do that?

    Thanks
    There is no in-vivo evidence that nettle or divanil can lower shbg and/or raise free test

    divanil has an estrogenic like structure, which i suspect is why it binds to shbg. however, this estrogenic structure may also cause it to stimulate shbg production in the liver.

    also, the well known product which was supposed to have divanil in it was found to contain almost no divanil.

    so divanil is nothing but an unproven theory
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  4.  06-18-2012  11:02 PM
    Registered User coolbreeze's Avatar
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    Originally Posted by Patrick Arnold View Post
    There is no in-vivo evidence that nettle or divanil can lower shbg and/or raise free test

    divanil has an estrogenic like structure, which i suspect is why it binds to shbg. however, this estrogenic structure may also cause it to stimulate shbg production in the liver.

    also, the well known product which was supposed to have divanil in it was found to contain almost no divanil.

    so divanil is nothing but an unproven theory
    Ok, nix the nettle - what is left Pat?

  5.  06-20-2012  01:42 PM
    Registered User juverulez's Avatar
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    Vitex might be an option

  6.  06-21-2012  09:06 PM
    Registered User Force of Green's Avatar
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    Originally Posted by juverulez View Post
    Vitex might be an option
    I thought that Vitex would be good for prolactin control. Then again, that's only going from what I read in forums and product descriptions/writeups.

  7.  06-21-2012  09:12 PM
    Registered User Uziel's Avatar
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    Originally Posted by Patrick Arnold View Post
    There is no in-vivo evidence that nettle or divanil can lower shbg and/or raise free test

    divanil has an estrogenic like structure, which i suspect is why it binds to shbg. however, this estrogenic structure may also cause it to stimulate shbg production in the liver.

    also, the well known product which was supposed to have divanil in it was found to contain almost no divanil.

    so divanil is nothing but an unproven theory
    Planta Med. 1997 Dec;63(6):529-32.
    Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG)

  8.  06-21-2012  10:23 PM
    Featured Author Patrick Arnold's Avatar
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    Originally Posted by Uziel View Post
    Planta Med. 1997 Dec;63(6):529-32.
    Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG)

    lignans are estrogenic, and estrogens bind quite well to shbg, so this does not come as much surprise


    "The lignans are a group of chemical compounds found in plants. Lignans are one of the major classes of phytoestrogens, which are estrogen-like chemicals and also act asantioxidants. The other classes of phytoestrogens are the isoflavones and coumestans"

    http://en.wikipedia.org/wiki/Lignans


    Do u think ingesting phytoestrogens is a smart way to increase testosterone?
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  9.  06-22-2012  01:30 PM
    Registered User RD929's Avatar
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    Originally Posted by Patrick Arnold View Post
    There is no in-vivo evidence that nettle or divanil can lower shbg and/or raise free test

    divanil has an estrogenic like structure, which i suspect is why it binds to shbg. however, this estrogenic structure may also cause it to stimulate shbg production in the liver.

    also, the well known product which was supposed to have divanil in it was found to contain almost no divanil.

    so divanil is nothing but an unproven theory
    Whaaa? Wait did this product start with an A and originally have lightning bolts on the label?

  10.  06-22-2012  03:38 PM
    Registered User Force of Green's Avatar
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    Originally Posted by RD929 View Post
    Whaaa? Wait did this product start with an A and originally have lightning bolts on the label?
    Activate is probably the most well-known Divanil product... Even though there are many others now.

  11.  06-22-2012  11:25 PM
    Registered User Uziel's Avatar
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    Originally Posted by Patrick Arnold View Post
    lignans are estrogenic, and estrogens bind quite well to shbg, so this does not come as much surprise


    "The lignans are a group of chemical compounds found in plants. Lignans are one of the major classes of phytoestrogens, which are estrogen-like chemicals and also act asantioxidants. The other classes of phytoestrogens are the isoflavones and coumestans"

    http://en.wikipedia.org/wiki/Lignans


    Do u think ingesting phytoestrogens is a smart way to increase testosterone?
    i only use Nettle (3,4-divanillyltetrahydrofuran + 6,7-divanillyltetrahydrofuran) for block the binding of dht at the prostate no more Sir.

  12.  06-23-2012  06:45 AM
    Registered User RD929's Avatar
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    Originally Posted by Force of Green View Post
    Activate is probably the most well-known Divanil product... Even though there are many others now.
    I thought we weren't playing the name game for the sake of safety when it came to the earlier statement. Oh well. Yea I would be upset if that was what he was talking about the well known product that actually had no divanil

  13.  06-27-2012  10:59 AM
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    Originally Posted by coolbreeze View Post
    Ok, nix the nettle - what is left Pat?
    Hey PA is there anything to run with DAA to boost free test?

  14.  06-27-2012  11:06 AM
    Featured Author Patrick Arnold's Avatar
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    Originally Posted by koi1214 View Post
    Hey PA is there anything to run with DAA to boost free test?
    dunno of anything proven to "free up" bound testosterone in the blood that wont also result in HPTA suppression and/or increased SHBG production
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