omeprazole and mineral absorption?

  1. Elite Member
    MAxximal's Avatar
    Stats
    5'11"  235 lbs.
    Join Date
    Jan 2009
    Age
    37
    Posts
    6,901
    Rep Power
    122082
    Level
    55
    Lv. Percent
    25.35%
    Achievements Activity ProPosting ProPosting Authority
    SNS Online Representative
    Maxximal @ seriousnutritionsolutions.com

    Got Glycophase ...?



  2. Elite Member
    MAxximal's Avatar
    Stats
    5'11"  235 lbs.
    Join Date
    Jan 2009
    Age
    37
    Posts
    6,901
    Rep Power
    122082
    Level
    55
    Lv. Percent
    25.35%
    Achievements Activity ProPosting ProPosting Authority

    any ideas?
    SNS Online Representative
    Maxximal @ seriousnutritionsolutions.com

    Got Glycophase ...?


  3. Featured Author
    dinoiii's Avatar
    Join Date
    Dec 2006
    Posts
    691
    Rep Power
    4097
    Level
    20
    Lv. Percent
    85.96%

    I am unsure what kind of ideas you are looking for here.

    A proton pump inhibitor (PPI), like omeprazole (Nexium), or Prilosec, or Zegerid, or Protonix will, in fact, have some absorption issues. Vitamin B12 is a much bigger issue in absorption coupled with a PPI than are minerals due to acid requirements for Intrinsic Factor complex coupling. People will use them freely though unfortunately.

    At the same time, you can alter your mineral intake (at a different time of the day - minimum 6-8 hours apart from a PPI) to gain better absorption while on your medication course. That's not to say you won't get any absorption issues still. You just have to understand the pharmacokinetics: The elimination half-life of PPIs ranges from 0.5–2 hours, however the effect of a single dose on acid secretion usually persists up to 2–3 days. This is because of accumulation of the drug in parietal cell canaliculi and the irreversible nature of proton pump inhibition.

    Mind you, you should NOT use them continuously unless you have some documented case of Peptic Ulcer Disease. Otherwise, they should only be used for a brief period (defined as 14 days or less) and at a duration NO LONGER than 3 times per year. That would be - at its MAX - 42 days out of a 365-day year if you were considering 3 two-week cycles per year. If your doctor has not documented Peptic Ulcer Disease but yet has assigned you to a PPI for longer than this timeframe, it may be time to re-consider your physician choice. If you are self-medicating as there are so many of these things OTC now-a-days, then seek the help of a qualified healthcare professional.


    D_
    Anabolicminds.com Featured Author
    •   
       

  4. Elite Member
    MAxximal's Avatar
    Stats
    5'11"  235 lbs.
    Join Date
    Jan 2009
    Age
    37
    Posts
    6,901
    Rep Power
    122082
    Level
    55
    Lv. Percent
    25.35%
    Achievements Activity ProPosting ProPosting Authority

    Thanks D but I not use it my wife has a Hiatal Hernia and was prescribed with omeprazole.
    SNS Online Representative
    Maxximal @ seriousnutritionsolutions.com

    Got Glycophase ...?


  5. Featured Author
    dinoiii's Avatar
    Join Date
    Dec 2006
    Posts
    691
    Rep Power
    4097
    Level
    20
    Lv. Percent
    85.96%

    Quote Originally Posted by MAxximal View Post
    Thanks D but I not use it my wife has a Hiatal Hernia and was prescribed with omeprazole.
    How long has she used it?

    Even hiatal hernia isn't really an indication for lifelong use. If her doctor does not revisit this, we know one is for sure...fracture risk goes up with longer than a 2-year usage and moreso with > 4 years (likely secondary to calcium absorption issues); but long-term use has failed to produce studies of support.

    I am convinced that surgical correction of hiatal hernias play a bigger role in long-term therapy though there is a dearth of literature in either direction.

    Does she supplement with any kind of mineral supplements?



    D_
    Anabolicminds.com Featured Author
  

  
 

Similar Forum Threads

  1. P-Plex and Mineral Imbalance
    By bigzach1234 in forum Anabolics
    Replies: 1
    Last Post: 05-17-2011, 11:27 AM
  2. Case Against Vitamin and Mineral Ban
    By Dwight Schrute in forum News and Articles
    Replies: 0
    Last Post: 01-31-2005, 02:31 AM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Log in
Log in