36yo On Clomid For 2 Years

[cajuntx]

Hello,

I've been taking 25mg of Clomid EOD for about 2 years now. I haven't had any side effects, and feel good, so far. I had blood work done last year, and everything was good. However, I did notice a big increase in E2 level, so take Calicium D-Glucarate and IC3 ED. Also, take Boron and Nettle Root Extract. I plan on getting blood done next month. My question is really about safety. I read somewhere that clomiphene can be carcinogenic. What does this mean?
Also, the reason I'm taking is due to low testosterone levels, but my wife and I aren't done having kids. She's actually pregnant now with our first baby girl - due this April. A doctor suggested pellets, but again, how does that impact sperm production?

Anyway, I just want to make sure I'm not putting my health at risk with long-term Clomid use. I considered TRT, but don't think it's the best option for me since we're still wanting more kids. Is Clomid the best solution in 2018? I read something about Androxal (enclomiphene), but apparently it didn't make it past trials, and FDA didn't approve. I did find that a pharma company in India produces an enclomiphene variant, but it's a little sketch. I wouldn't trust the source without lab testing. A source in EU told me they don't sell it, so it's pretty much unavailable/unobtainable.

Also, I'm very active and do bodybuilding/powerlifting. My strength has been pretty good on Clomid - currently deadlifting 545 lbs. and squatting 425 lbs. - which is pretty good for a tall guy (6'4"). I just want to keep my hormones in check, but don't want to jeopardize sperm production. I don't take anything else aside from Clomid and herbal supps. Any advice is much appreciated!

Thanks!

 

[mrhappyoz]

Low testosterone can have a number of causes. You may be able to resolve this issue a different way, with some blood work and diagnostics.

Common causes -
Insufficient sleep / high cortisol
Insufficient dietary fat - no cholesterol to build T from
Low dietary iodine intake
.. others

Do any of these have potential, so far?

 

[kenpoengineer]

http://www.peaktestosterone.com/Clomid_Risk.aspx

 

[kenpoengineer]

https://www.excelmale.com/showthread.php?435-The-Use-of-HCG-to-Prevent-Reverse-Testicular-Shrinkage-and-Preserve-Fertility

 

[cajuntx]

My sleep is really good (8-9 hours), and stress is minimum. I watch my diet (count macros) and keep my fats around 20-24% of total cals. I don't believe my iodine levels would be low (eat cheese, fruits, veggies, and take multi). My test levels drop from 700s to 200s when stopping Clomid (taking EOD 25mg).

 

[cajuntx]

Right, so it's basically unknown for those of us taking low dosages (25mg EOD or 12.5mg ED). I couldn't find the dosage administered to the rabbits in that one study cited (would be good to know ratio/amount given and for how long). I get vision checked every year, so far no issues. I don't have any of the side effects mentioned in that article. I'm guessing they've taken higher dosages? I realize long-term side effects are unknown since not a lot of studies have been done, which is a shame. That being said, if not Clomid, and if wanting to preserve fertility, what else do men have? I don't see a lot of options. I know HCG is an option, but isn't exactly the most affordable route. I've heard that you can take TRT to keep levels within normal range, and it'll take 3-9 months after stopping for spermatogenesis to return, but still, not 100% on that, and of course if you exceed normal range it's even more speculative as whether it'll ever return.

 

[mrhappyoz]

Got blood work you can share?

 

[John Smeton]

If bloodwork drops every time you get off clomid then you have hypogonadism and are a candidate for trt . Thats the problem with many people that do clomid , hcg, and ai and test is good. Its when they are poff everything that tells the real story. My endo tested me five times over a two year period and made me stay off anything that would raise test. Im glad he did.

 

[kenpoengineer]

If bloodwork drops every time you get off clomid then you have hypogonadism and are a candidate for trt . Thats the problem with many people that do clomid , hcg, and ai and test is good. Its when they are poff everything that tells the real story. My endo tested me five times over a two year period and made me stay off anything that would raise test. Im glad he did.

Good advice. HPTA Restart protocol using Clomid then HCG is usually what a good doctor will prescribe to protect you from a life of injections, ton of bloodwork and blood donations that IS TRT. If that doesn’t work then TRT is warranted.

 

[Spurfy]

Hello,

I've been taking 25mg of Clomid EOD for about 2 years now. I haven't had any side effects, and feel good, so far. I had blood work done last year, and everything was good. However, I did notice a big increase in E2 level, so take Calicium D-Glucarate and IC3 ED. Also, take Boron and Nettle Root Extract. I plan on getting blood done next month. My question is really about safety. I read somewhere that clomiphene can be carcinogenic. What does this mean?
Also, the reason I'm taking is due to low testosterone levels, but my wife and I aren't done having kids. She's actually pregnant now with our first baby girl - due this April. A doctor suggested pellets, but again, how does that impact sperm production?

Anyway, I just want to make sure I'm not putting my health at risk with long-term Clomid use. I considered TRT, but don't think it's the best option for me since we're still wanting more kids. Is Clomid the best solution in 2018? I read something about Androxal (enclomiphene), but apparently it didn't make it past trials, and FDA didn't approve. I did find that a pharma company in India produces an enclomiphene variant, but it's a little sketch. I wouldn't trust the source without lab testing. A source in EU told me they don't sell it, so it's pretty much unavailable/unobtainable.

Also, I'm very active and do bodybuilding/powerlifting. My strength has been pretty good on Clomid - currently deadlifting 545 lbs. and squatting 425 lbs. - which is pretty good for a tall guy (6'4"). I just want to keep my hormones in check, but don't want to jeopardize sperm production. I don't take anything else aside from Clomid and herbal supps. Any advice is much appreciated!

Thanks!

Aromasin at 6.25 E3D would be a perfect compliment to your Clomid use. I've used this before while on Clomid-only, kept E2 around 35 and gave a nice bump to free T.

 

[BBiceps]

I was on TRT for little more than 2 yrs and during this time my wife and I realized we wanted another kid, unfortunately my sperm was “too low to measure”. I stopped the test and went on Clomid&HCG for about 2 months and I was back and my wife got pregnant.

So, if you still want kids you should hold off on TRT. I do a 4-8 week Clomid “cycle” 1 or 2 times a year to keep my levels above 400-500 and fill fine... I do miss the test though