I have done a lot of research on endurance enhancing supplements and would love some feedback on EPO and or Aicar if anyone has run these. thanks
The OP was not asking about ALCAR (acetyl-l-carnitine).
He was comparing two peptides. EPO and AICAR (i not L).
AICAR, aminoimidazole carboxamide ribonucleotide, acts as an agonist to AMP-activated protein kinase; AMP-activated protein kinase, also known as AMPK, is an enzyme with an important role in cellular homeostasis and energy regulation. AMPK acts through a variety of means to ultimately stimulate liver fatty oxidation, ketogenesis, beta-cell modulation of insulin secretion, and other functions within the body. AICAR has been shown to stimulate glucose uptake and reduce apoptosis by reducing reactive oxygen compounds within cells.
Just did a couple of quick reads on this stuff.
Hey, Fish , try them both and let us know how they worked for you. You're the man.
I haven't tried either. I'm afraid of anything that will raise hematocrit, since I am on TRT. EPO does seem dangerous in this regard.
From my readings though, I wonder how AICAR can increase endurance. It seems like it'd be better used while cutting or trying to lose weight, although I am sure it does more than what I posted. I just came across that info the other day. it's totally new to me
Did some more quick checks on Aicar, and it was produced to attempt to get the effects of endurance exercise by non-exercisers. Test show that it doesn't work that way on mice and other small animals, but if they do regularly exercise it increases their abilities dramatically -- for small rodents anyway. Yet it seems even more effective to lose weight. There have apparently been humans that have "pioneered" in this weight loss area and gotten great results. Pioneers as we all know often get arrows in their backs, as nobody understands the potential long-term effects this may have.
I don't mind Efish testing this stuff out for us, but I will pass. I really believe he's just trying to show people that he's "cutting edge" on these peptides. I learned a few new facts anyway.